Unique and overlapping GLI1 and GLI2 transcriptional targets in neoplastic chondrocytes
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0211333
Abstract: Excessive Hedgehog (Hh) signaling in chondrocytes is sufficient to cause formation of enchondroma-like lesions which can progress to chondrosarcoma. To elucidate potential underlying mechanisms, we identified GLI1 and GLI2 target genes in human chondrosarcoma. Using… read more here.
Keywords: gli1 gli2; neoplastic chondrocytes; unique overlapping; gli2 transcriptional ... See more keywords