Intravitreal ranibizumab versus aflibercept following treat and extend protocol for neovascular age-related macular degeneration
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DOI: 10.1007/s00417-019-04360-9
Abstract: PurposeTo assess the morphological and functional outcome and stability of the “treat and extend” protocol using aflibercept compared to ranibizumab for the treatment of eyes with neovascular age-related macular degeneration.Patients and methodsThis retrospective study included… read more here.
Keywords: age related; treatment; extend protocol; group ... See more keywords
Neovascular age-related macular degeneration presenting at extremities of age: a comparative study
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DOI: 10.1007/s00417-020-04893-4
Abstract: To compare the characteristics and response to treatment between patients with NVAMD presenting at the extremities of the AMD age spectrum. Fifty-four eyes of 47 patients were included in this retrospective study, divided by age… read more here.
Keywords: age related; related macular; age; study ... See more keywords
Prechoroidal cleft thickness correlates with disease activity in neovascular age-related macular degeneration
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DOI: 10.1007/s00417-021-05384-w
Abstract: The purpose of this study was to investigate the structural variations of the hyporeflective pocket of fluid (prechoroidal cleft) located between Bruch’s membrane and the hyperreflective material within the pigment epithelial detachment (PED) in patients… read more here.
Keywords: prechoroidal cleft; cleft; mnv; activity ... See more keywords
Effects of delay in anti-vascular endothelial growth factor intravitreal injections for neovascular age-related macular degeneration
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DOI: 10.1007/s00417-021-05505-5
Abstract: Purpose To assess the impact of COVID-19-related delay in intravitreal injection timing on macular structure and visual acuity (VA) among patients treated for neovascular age-related macular degeneration (nvAMD). Methods We reviewed demographic and clinical data… read more here.
Keywords: eyes group; group; group eyes; age related ... See more keywords
Efficacy of treat-and-extend regimen with aflibercept for pachychoroid neovasculopathy and Type 1 neovascular age-related macular degeneration
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DOI: 10.1007/s10384-018-0562-0
Abstract: PurposeTo evaluate the efficacy of intravitreal aflibercept therapy using a treat-and-extend regimen on treatment-naïve pachychoroid neovasculopathy (PNV) and Type 1 neovascular age-related macular degeneration (AMD).MethodsWe retrospectively studied 42 eyes with PNV and 60 eyes with… read more here.
Keywords: pachychoroid neovasculopathy; extend regimen; polypoidal lesions; type neovascular ... See more keywords
Visual acuity outcomes of anti-VEGF treatment for neovascular age-related macular degeneration in clinical trials
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DOI: 10.1007/s10384-021-00869-x
Abstract: Anti-VEGF treatment for neovascular age-related macular degeneration (nAMD) has been evaluated in clinical trials. To select the best anti-VEGF drug and the best treatment regimen for nAMD, a thorough understanding of the characteristics of each… read more here.
Keywords: anti vegf; treatment; treatment neovascular; vegf treatment ... See more keywords
Switching from aflibercept to brolucizumab for the treatment of refractory neovascular age-related macular degeneration
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DOI: 10.1007/s10384-022-00908-1
Abstract: To examine the 16-week outcomes of switching to brolucizumab in eyes with neovascular age-related macular degeneration (nAMD) refractory to aflibercept. Retrospective observational study. Data of eyes with nAMD who switched to brolucizumab because of resistance… read more here.
Keywords: refractory; age related; macular degeneration; treatment ... See more keywords
Three-Year Outcomes of Aflibercept Treatment for Neovascular Age-Related Macular Degeneration: Evidence from a Clinical Setting
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DOI: 10.1007/s40123-018-0139-5
Abstract: IntroductionTo report 3-year treatment outcomes with intravitreal aflibercept injections for neovascular age-related macular degeneration (nAMD) in routine clinical practice.MethodsThis was a retrospective, single-centre, non-randomized interventional case series analysis. Data from treatment-naïve patients with nAMD treated… read more here.
Keywords: age related; related macular; treatment; year ... See more keywords
Gene Therapy in Neovascular Age-related Macular Degeneration: Three-Year Follow-up of a Phase 1 Randomized Dose Escalation Trial.
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DOI: 10.1016/j.ajo.2017.02.018
Abstract: PURPOSE To assess the safety of rAAV.sFlt-1 subretinal injection in neovascular age-related macular degeneration (wet AMD) over 36 months. DESIGN Phase 1 dose escalation trial. METHODS Eight subjects with advanced, treatment-experienced wet AMD were randomly assigned… read more here.
Keywords: macular degeneration; age related; related macular; wet amd ... See more keywords
Geographic access disparities of clinical trials in neovascular age-related macular degeneration in the United States.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2021.04.001
Abstract: PURPOSE To identify geographic and socioeconomic variables predictive of residential proximity to neovascular age-related macular degeneration (nAMD) clinical trial locations. DESIGN Retrospective, cross-sectional study. METHODS Census-tract level data from public datasets and trial-level data from… read more here.
Keywords: trial; macular degeneration; age related; related macular ... See more keywords
Predictors of good visual outcomes in patients with neovascular age-related macular degeneration in daily practice.
Sign Up to like & getrecommendations! Published in 2020 at "Journal francais d'ophtalmologie"
DOI: 10.1016/j.jfo.2020.02.032
Abstract: PURPOSE To report predictive factors for therapeutic response to anti-VEGF in patients with neovascular age-related macular degeneration (nAMD) in daily clinical practice in our patient population. METHODS Retrospective cohort study including 56 patients (69 eyes)… read more here.
Keywords: anti vegf; patients neovascular; macular degeneration; age related ... See more keywords