Lutein and zeaxanthin attenuates VEGF-induced neovascularisation in human retinal microvascular endothelial cells through a Nox4-dependent pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108104
Abstract: Age-related macular degeneration (AMD) and proliferative diabetic retinopathy (DR) are two of the most common and severe causes of vision loss in the population. Both conditions are associated with excessive levels of vascular endothelial growth… read more here.
Keywords: retinal microvascular; induced neovascularisation; vegf induced; lutein zeaxanthin ... See more keywords
Inhibition of prolyl hydroxylase domain proteins selectively enhances venous thrombus neovascularisation.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis research"
DOI: 10.1016/j.thromres.2018.07.015
Abstract: BACKGROUND Hypoxia within acute venous thrombi is thought to drive resolution through stabilisation of hypoxia inducible factor 1 alpha (HIF1α). Prolyl hydroxylase domain (PHD) isoforms are critical regulators of HIF1α stability. Non-selective inhibition of PHD… read more here.
Keywords: resolution; phd; thrombus resolution; venous thrombus ... See more keywords
Supplemental Anti Vegf A-Therapy Prevents Rebound Neovascularisation After Fine Needle Diathermy Treatment to Regress Pathological Corneal (LYMPH)Angiogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-60705-z
Abstract: Fine needle diathermy (FND) is an effective method to destroy and regress pathologic corneal blood and lymphatic vessels. However, it is unknown whether FND itself causes a rebound corneal neovascularisation and whether that can be… read more here.
Keywords: corneal; vegf; treatment; fine needle ... See more keywords
[Choroidal Neovascularisation Other than Typical Neovascular Age-Related Macular Degeneration].
Sign Up to like & getrecommendations! Published in 2018 at "Klinische Monatsblatter fur Augenheilkunde"
DOI: 10.1055/s-0042-123833
Abstract: Choroidal neovascularisation (CNV) in the context of exsudative age-related macular degeneration (nAMD) can be divided into type 1 (occult) and type 2 (classical) membranes. Retinal angiomatous proliferation (RAP) or polypoidal choroidal vasculopathy (PCV) are "rare… read more here.
Keywords: choroidal neovascularisation; choroidal; age related; related macular ... See more keywords
Intravitreal aflibercept for idiopathic choroidal neovascularisation in paediatric age
Sign Up to like & getrecommendations! Published in 2023 at "BMJ Case Reports"
DOI: 10.1136/bcr-2022-252270
Abstract: A boy in early adolescence presented with a 1-week history of visual acuity impairment in his right eye (RE). Fundus examination of the RE revealed an elevated yellow-greyish lesion in the inferior temporal juxtafoveolar area.… read more here.
Keywords: aflibercept idiopathic; choroidal neovascularisation; neovascularisation; idiopathic choroidal ... See more keywords
‘Dye-less’ angiography of diabetic retinal neovascularisation
Sign Up to like & getrecommendations! Published in 2019 at "Postgraduate Medical Journal"
DOI: 10.1136/postgradmedj-2019-136560
Abstract: A 61-year-old man presented with floaters in his right eye for the past 2 weeks. He had a history of poorly controlled type 2 diabetes mellitus for the past 16 years along with deranged renal… read more here.
Keywords: neovascularisation; retinal neovascularisation; less angiography; angiography diabetic ... See more keywords
Behaviour of CD11b-Positive Cells in an Animal Model of Laser-Induced Choroidal Neovascularisation
Sign Up to like & getrecommendations! Published in 2017 at "Ophthalmologica"
DOI: 10.1159/000453550
Abstract: Background/Aim: Immune cells, e.g. microglial cells of the retina, appear to be involved in pathological processes in neovascular age-related macular degeneration. Therefore, the purpose of this study was to immunohistochemically check the expression of various… read more here.
Keywords: laser; animal model; cd11b positive; cd11b ... See more keywords
Long-term outcomes of high-dose conbercept treatment for myopic cho-roidal neovascularisation and idiopathic choroidal neovascularisation.
Sign Up to like & getrecommendations! Published in 2023 at "Ophthalmic research"
DOI: 10.1159/000529342
Abstract: INTRODUCTION To report 2-year outcomes of intravitreal injection of high-dose conbercept (1 mg 2+PRN scheme) for subjects with myopic choroidal neovascularization (mCNV) and idiopathic choroidal neovascularization (iCNV) by optical coherence tomography angi-ography (OCTA) follow-up. METHODS… read more here.
Keywords: neovascularisation; idiopathic choroidal; group; dose conbercept ... See more keywords
Intraplaque neovascularisation is associated with ischaemic events after carotid artery stenting: an observational prospective study
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic Advances in Neurological Disorders"
DOI: 10.1177/17562864221141133
Abstract: Background: Intraplaque neovascularisation (IPN) is a component of vulnerable atherosclerotic plaque, which is a biomarker of cardiovascular events. However, the identification of patients with high probability of ischaemic events after carotid artery stenting (CAS) is… read more here.
Keywords: neovascularisation; ischaemic events; carotid artery; risk ... See more keywords
Neuropilin 1 Involvement in Choroidal and Retinal Neovascularisation
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DOI: 10.1371/journal.pone.0169865
Abstract: Purpose Inhibiting VEGF is the gold standard treatment for neovascular age-related macular degeneration (AMD). It is also effective in preventing retinal oedema and neovascularisation (NV) in diabetic retinopathy (DR) and retinal vein occlusions (RVO). Neuropilin… read more here.
Keywords: retinal neovascularisation; nrp1; neuropilin involvement; choroidal retinal ... See more keywords
Matrix Metalloproteinase 10 Contributes to Choroidal Neovascularisation
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10071557
Abstract: Age-related macular degeneration (AMD) is currently the main cause of severe visual loss among older adults in developed countries. The pathophysiology has not been clarified, but oxidative stress is believed to play a major role.… read more here.
Keywords: choroidal neovascularisation; neovascularisation; role; metalloproteinase contributes ... See more keywords