Retinal Avascularity and Neovascularization Associated With LAMA1 (laminin1) Mutation in Poretti-Boltshauser Syndrome.
Sign Up to like & getrecommendations! Published in 2018 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.5060
Abstract: Retinal Avascularity and Neovascularization Associated With LAMA1 (laminin1) Mutation in Poretti-Boltshauser Syndrome Poretti-Boltshauser syndrome (PBS) is caused by LAMA1 (laminin1) (OMIM 150320) mutations and manifests with neurologic and ocular abnormalities, including retinal abnormalities previously described… read more here.
Keywords: poretti boltshauser; boltshauser syndrome; neovascularization; lama1 laminin1 ... See more keywords
Correlation of Optical Coherence Tomography Angiography of Type 3 Macular Neovascularization With Corresponding Histology.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2022.0890
Abstract: Importance By validating optical coherence tomography angiography (OCTA) in the analysis of type 3 macular neovascularization secondary to age-related macular degeneration, the overall value of clinical OCTA for disease observation, diagnosis, and staging is increased.… read more here.
Keywords: octa; eye; histology; type macular ... See more keywords
A Novel “Inside‐Out” Intraocular Nanomedicine Delivery Mode for Nanomaterials’ Biological Effect Enhanced Choroidal Neovascularization Occlusion and Microenvironment Regulation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202209690
Abstract: Photodynamic therapy (PDT) is commonly used in choroidal neovascularization (CNV) treatment due to the superior light transmittance of the eye. However, PDT often leads to surrounding tissue damage and further microenvironmental deterioration, including exacerbated hypoxia,… read more here.
Keywords: microenvironment; cnv; occlusion; choroidal neovascularization ... See more keywords
Classification of neovascularization on retinal images using extreme learning machine
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Imaging Systems and Technology"
DOI: 10.1002/ima.22529
Abstract: Proliferative diabetic retinopathy is the advanced stage of diabetic retinopathy (DR) resulting in the growth of abnormal vessels on the retinal surface termed as neovascularization. This article primarily deals with the timely detection and classification… read more here.
Keywords: classification; extreme learning; using extreme; learning machine ... See more keywords
In situ ultrasound imaging of silk hydrogel degradation and neovascularization
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1981
Abstract: Ultrasound (US) is a useful technique to monitor morphological and functional changes of biomaterial implants without sacrificing the animal. Contrast‐enhanced ultrasound (CEUS) along with two‐dimensional (2D) US were used to characterize the biodegradation and neovascularization… read more here.
Keywords: degradation; vascularization; silk; neovascularization ... See more keywords
Intrastromal bevacizumab in the management of corneal neovascularization: a retrospective review
Sign Up to like & getrecommendations! Published in 2019 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-019-04519-4
Abstract: Purpose To evaluate the long-term safety and efficacy of intrastromal bevacizumab for treatment of deep corneal neovascularization in candidates for high-risk cornea grafting. Methods A single-center retrospective study involving 14 eyes of 14 patients with… read more here.
Keywords: corneal; intrastromal bevacizumab; bevacizumab management; corneal neovascularization ... See more keywords
Assessing the long-term evolution of type 3 neovascularization in age-related macular degeneration using optical coherence tomography angiography
Sign Up to like & getrecommendations! Published in 2021 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-021-05163-7
Abstract: To analyze the evolution of type 3 neovascularization in eyes with age-related macular degeneration during anti-vascular endothelial growth factor (VEGF) treatment using optical coherence tomography angiography (OCTA) analysis. Forty-one treatment-naïve eyes (37 patients) with type… read more here.
Keywords: age related; related macular; evolution type; type neovascularization ... See more keywords
Glycopeptide-nanotransforrs eyedrops with enhanced permeability and retention for preventing fundus neovascularization.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.121361
Abstract: Efficient and non-invasive drug delivery to the fundus has always been a medical difficulty. Here, a co-assembled glycopeptide nanotransforrs (GPNTs) named MRP@DOX as a drug delivery system is reported. The MRP@DOX co-assemble nanoparticles consisting of… read more here.
Keywords: nanotransforrs eyedrops; retention; neovascularization; mrp dox ... See more keywords
FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.01.014
Abstract: Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration. Using a mouse model of hypoxia-driven retinal neovascularization, we find that fibroblast growth factor 21 (FGF21)… read more here.
Keywords: choroidal neovascularization; fgf21 administration; administration suppresses; neovascularization ... See more keywords
A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization
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DOI: 10.1016/j.celrep.2019.08.073
Abstract: SUMMARY Id helix-loop-helix (HLH) proteins (Id1–4) bind E protein bHLH transcription factors, preventing them from forming active transcription complexes that drive changes in cell states. Id proteins are primarily expressed during development to inhibit differentiation,… read more here.
Keywords: ocular neovascularization; pan antagonist; small molecule; molecule pan ... See more keywords
Silencing of galectin‐1 inhibits retinal neovascularization and ameliorates retinal hypoxia in a murine model of oxygen‐induced ischemic retinopathy
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2017.02.015
Abstract: Abstract Aberrant neovascularization is a consequence of inappropriate angiogenic signaling and contributes to several diseases. Although many regulators of pathogenic angiogenesis have been identified, the understanding of this process remains incomplete. Galectin‐1 (Gal‐1), as a… read more here.
Keywords: retinal hypoxia; gal; model; neovascularization ... See more keywords