Retinal Avascularity and Neovascularization Associated With LAMA1 (laminin1) Mutation in Poretti-Boltshauser Syndrome.
Sign Up to like & getrecommendations! Published in 2018 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.5060
Abstract: Retinal Avascularity and Neovascularization Associated With LAMA1 (laminin1) Mutation in Poretti-Boltshauser Syndrome Poretti-Boltshauser syndrome (PBS) is caused by LAMA1 (laminin1) (OMIM 150320) mutations and manifests with neurologic and ocular abnormalities, including retinal abnormalities previously described… read more here.
Keywords: poretti boltshauser; boltshauser syndrome; neovascularization; lama1 laminin1 ... See more keywords
Correlation of Optical Coherence Tomography Angiography of Type 3 Macular Neovascularization With Corresponding Histology.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2022.0890
Abstract: Importance By validating optical coherence tomography angiography (OCTA) in the analysis of type 3 macular neovascularization secondary to age-related macular degeneration, the overall value of clinical OCTA for disease observation, diagnosis, and staging is increased.… read more here.
Keywords: octa; eye; histology; type macular ... See more keywords
Hierarchically Structured Biodegradable Microspheres Promote Therapeutic Angiogenesis
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202401832
Abstract: Promoting neovascularization is a prerequisite for many tissue engineering applications and the treatment of cardiovascular disease. Delivery of a pro‐angiogenic stimulus via acellular materials offers several benefits over biological therapies but has been hampered by… read more here.
Keywords: neovascularization; microspheres promote; biodegradable microspheres; hierarchically structured ... See more keywords
A Novel “Inside‐Out” Intraocular Nanomedicine Delivery Mode for Nanomaterials’ Biological Effect Enhanced Choroidal Neovascularization Occlusion and Microenvironment Regulation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202209690
Abstract: Photodynamic therapy (PDT) is commonly used in choroidal neovascularization (CNV) treatment due to the superior light transmittance of the eye. However, PDT often leads to surrounding tissue damage and further microenvironmental deterioration, including exacerbated hypoxia,… read more here.
Keywords: microenvironment; cnv; occlusion; choroidal neovascularization ... See more keywords
Engineered Neutrophil Nanovesicles for Inhibiting Corneal Neovascularization by Synergistic Anti‐Inflammatory, Anti‐VEGF, and Chemoexcited Photodynamic Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Materials"
DOI: 10.1002/adma.202411030
Abstract: Corneal neovascularization (CorNV) develops under various pathological conditions and is one of the main causes of blindness. Due to that CorNV progression involves multiple steps, anti‐vascular endothelial growth factor (VEGF) drugs alone could not sufficiently… read more here.
Keywords: neovascularization; corneal neovascularization; cornv; chemoexcited photodynamic ... See more keywords
Immune Checkpoint PD‐L1 Modulates Retinal Microglial Activation to Alleviate Vascular Leakage in Choroidal Neovascularization via ERK
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202400747
Abstract: Neovascular age‐related macular degeneration (NVAMD) is a common retinal disease causing vision loss in the elderly. Neuroinflammation significantly contributes to NVAMD's etiology. This study explores the role of Programmed cell death ligand 1 (PD‐L1), an… read more here.
Keywords: neovascularization; vascular leakage; immune checkpoint; neovascularization via ... See more keywords
Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti-VEGFA Nanobody and Proprietary Penetratin Analog Formulation.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202504660
Abstract: Pathological retinal and choroidal neovascularization is a hallmark of several blinding diseases, including diabetic retinopathy and age‐related macular degeneration. While intravitreal anti‐VEGF therapies remain the standard of care, they necessitate frequent injections, posing risks such… read more here.
Keywords: neovascularization; anti vegfa; retinal choroidal; pathological retinal ... See more keywords
Classification of neovascularization on retinal images using extreme learning machine
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Imaging Systems and Technology"
DOI: 10.1002/ima.22529
Abstract: Proliferative diabetic retinopathy is the advanced stage of diabetic retinopathy (DR) resulting in the growth of abnormal vessels on the retinal surface termed as neovascularization. This article primarily deals with the timely detection and classification… read more here.
Keywords: classification; extreme learning; using extreme; learning machine ... See more keywords
In situ ultrasound imaging of silk hydrogel degradation and neovascularization
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1981
Abstract: Ultrasound (US) is a useful technique to monitor morphological and functional changes of biomaterial implants without sacrificing the animal. Contrast‐enhanced ultrasound (CEUS) along with two‐dimensional (2D) US were used to characterize the biodegradation and neovascularization… read more here.
Keywords: degradation; vascularization; silk; neovascularization ... See more keywords
Intrastromal bevacizumab in the management of corneal neovascularization: a retrospective review
Sign Up to like & getrecommendations! Published in 2019 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-019-04519-4
Abstract: Purpose To evaluate the long-term safety and efficacy of intrastromal bevacizumab for treatment of deep corneal neovascularization in candidates for high-risk cornea grafting. Methods A single-center retrospective study involving 14 eyes of 14 patients with… read more here.
Keywords: corneal; intrastromal bevacizumab; bevacizumab management; corneal neovascularization ... See more keywords
Assessing the long-term evolution of type 3 neovascularization in age-related macular degeneration using optical coherence tomography angiography
Sign Up to like & getrecommendations! Published in 2021 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-021-05163-7
Abstract: To analyze the evolution of type 3 neovascularization in eyes with age-related macular degeneration during anti-vascular endothelial growth factor (VEGF) treatment using optical coherence tomography angiography (OCTA) analysis. Forty-one treatment-naïve eyes (37 patients) with type… read more here.
Keywords: age related; related macular; evolution type; type neovascularization ... See more keywords