Neutrophil neprilysin expression correlates with inflammatory activation in chronic HFrEF patients
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DOI: 10.1093/ehjci/ehaa946.0937
Abstract: Inhibition of neprilysin by the angiotensin receptor-neprilysin inhibitor has shown remarkable success in the treatment of heart failure with reduced ejection fraction (HFrEF). However, the exact mechanism of action is still a matter of debate.… read more here.
Keywords: neutrophil nep; nep expression; hfref; expression ... See more keywords
Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis
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DOI: 10.1371/journal.pone.0189526
Abstract: Neprilysin (NEP, CD10) acts to limit excessive inflammation partly by hydrolyzing neuropeptides. Although deletion of NEP exacerbates intestinal inflammation in animal models, its role in ulcerative colitis (UC) is not well explored. Herein, we aimed… read more here.
Keywords: profound loss; ulcerative colitis; nep expression; loss ... See more keywords