Genetic analysis and outcomes of Omani children with steroid-resistant nephrotic syndrome.
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DOI: 10.1002/mgg3.2201
Abstract: BACKGROUND Nephrotic syndrome (NS) is one of the most common kidney disorders seen by pediatric nephrologists and is defined by the presence of heavy proteinuria (>3.5 g/24 h), hypoalbuminemia ( read more here.
Keywords: omani children; resistant nephrotic; syndrome; steroid resistant ... See more keywords
Acute kidney injury in patients with nephrotic syndrome undergoing contrast-enhanced CT for suspected venous thromboembolism: a propensity score-matched retrospective cohort study
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DOI: 10.1007/s00330-017-5109-0
Abstract: ObjectivesTo determine whether intravenous iodinated contrast material administration increases the risk of acute kidney injury (AKI) in patients with nephrotic syndrome undergoing contrast-enhanced CT.MethodsPatients with nephrotic syndrome undergoing contrast-enhanced CT were retrospectively identified (n =… read more here.
Keywords: kidney injury; contrast; acute kidney; contrast enhanced ... See more keywords
Does Zika virus infection induce prolonged remissions in children with idiopathic nephrotic syndrome?
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DOI: 10.1007/s00467-017-3588-5
Abstract: BackgroundZika is an emerging mosquito-borne flavivirus. We report two pediatric patients diagnosed with idiopathic nephrotic syndrome who achieved complete remission of the disease after suffering Zika virus (ZIKV) infection.Case Diagnosis/TreatmentThe first patient was a young… read more here.
Keywords: idiopathic nephrotic; zikv infection; infection; zika virus ... See more keywords
Impact of interrupted cyclosporine treatment on the development of chronic nephrotoxicity in children with steroid-dependent nephrotic syndrome
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DOI: 10.1007/s00467-017-3692-6
Abstract: Sir, We read with great interest the article titled BNephrotoxicity in children with frequently relapsing nephrotic syndrome receiving long-term cyclosporine treatment^ by Hamasaki et al. [1]. In a retrospective study on 36 patients with continuous… read more here.
Keywords: impact; treatment; csan patients; csa treatment ... See more keywords
The effect of vitamin D and calcium supplementation in pediatric steroid-sensitive nephrotic syndrome
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DOI: 10.1007/s00467-017-3716-2
Abstract: BackgroundLow serum levels of total 25-hydroxycholecalciferol (25(OH)D) occur in nephrotic syndrome (NS). We aimed to assess the effects of vitamin D3 and calcium supplementation on 25(OH)D levels, bone mineralization, and NS relapse rate in children… read more here.
Keywords: supplementation; vitamin calcium; steroid sensitive; vitamin ... See more keywords
Cost analysis on the use of rituximab and calcineurin inhibitors in children and adolescents with steroid-dependent nephrotic syndrome
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DOI: 10.1007/s00467-017-3789-y
Abstract: BackgroundRituximab (RTX) is increasingly being used in place of calcineurin inhibitors (CNI) in pediatric patients with steroid-dependent nephrotic syndrome (SDNS). However, despite its favorable safety profile, its unit cost is prohibitive. We therefore compared the… read more here.
Keywords: calcineurin inhibitors; group; dependent nephrotic; steroid dependent ... See more keywords
Uteroglobin gene polymorphism (G38A) may be a risk factor in childhood idiopathic nephrotic syndrome
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DOI: 10.1007/s00467-017-3800-7
Abstract: BackgroundUteroglobin (UG) is a multifunctional protein with anti-inflammatory properties. The aim of this study was to first evaluate the role of UG gene G38A polymorphism in childhood idiopathic nephrotic syndrome (INS), and determine whether this… read more here.
Keywords: childhood idiopathic; nephrology; idiopathic nephrotic; gene ... See more keywords
Nephrotic syndrome associated with severe hypertriglyceridemia in a pediatric patient: Answers
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DOI: 10.1007/s00467-018-3919-1
Abstract: 1. Hyperlipidemia is a characteristic feature of nephrotic syndrome (NS) with elevation of serum cholesterol and triglycerides (TG) [1]. However, due to the exceptionally high levels of serum TG (more than 2000 mg/dl), we further… read more here.
Keywords: syndrome associated; nephrotic syndrome; hypertriglyceridemia; deficiency ... See more keywords
Mycophenolate mofetil for sustained remission in nephrotic syndrome
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DOI: 10.1007/s00467-018-3970-y
Abstract: The clinical application of mycophenolate mofetil (MMF) has significantly widened beyond the prophylaxis of acute and chronic rejections in solid organ transplantation. MMF has been recognized as an excellent treatment option in many immunologic glomerulopathies.… read more here.
Keywords: sustained remission; remission; mmf; mycophenolate mofetil ... See more keywords
Treatment strategies for children with steroid-dependent nephrotic syndrome: in need of controlled studies
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DOI: 10.1007/s00467-018-4012-5
Abstract: Sir, In their letter to the Editor [1], Fujinaga and Sakuraya briefly report details of their single-center experience with steroidsparing agents for the treatment of steroid-dependent nephrotic syndrome (SDNS) in children [2]. The variety of… read more here.
Keywords: treatment; dependent nephrotic; steroid dependent; frns sdns ... See more keywords
Treatment of steroid-resistant nephrotic syndrome in the genomic era
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DOI: 10.1007/s00467-018-4093-1
Abstract: The pathogenesis of steroid-resistant nephrotic syndrome (SRNS) is not completely known. Recent advances in genomics have elucidated some of the molecular mechanisms and pathophysiology of the disease. More than 50 monogenic causes of SRNS have… read more here.
Keywords: treatment steroid; resistant nephrotic; nephrotic syndrome; steroid resistant ... See more keywords