214. THE EFFECT OF P2X7 ANTAGONISM ON NEPHROTOXIC NEPHRITIS
Sign Up to like & getrecommendations! Published in 2019 at "Rheumatology"
DOI: 10.1093/rheumatology/kez061.029
Abstract: Nephrotoxic nephritis (NTN) was induced in male WKY or P2X7 KO (on a WKY background) rats using a single IV injection of nephrotoxic serum. Animals were treated with one of two distinct P2X7 antagonists from… read more here.
Keywords: 214 effect; nephritis; nephrotoxic nephritis; day ... See more keywords
The lectin pathway does not contribute to glomerular injury in the nephrotoxic nephritis model.
Sign Up to like & getrecommendations! Published in 2021 at "Nephrology"
DOI: 10.1111/nep.13988
Abstract: AIMS Rapidly progressive crescentic glomerulonephritis occurs in a number systemic and primary glomerular diseases, including anti-glomerular basement membrane disease, anti-neutrophil cytoplasmic antibody vasculitis, and lupus nephritis. Our understanding of pathogenic mechanisms comes from animal models… read more here.
Keywords: nephrotoxic nephritis; lectin pathway; nephritis model; crescentic glomerulonephritis ... See more keywords