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   Articles with "nerve" as a keyword



TDP-43 Accumulation Within Intramuscular Nerve Bundles of Patients With Amyotrophic Lateral Sclerosis.

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recommendations! Published in 2022 at "JAMA neurology"

DOI: 10.1001/jamaneurol.2022.1113

Abstract: Importance Degeneration of neuromuscular junctions and axons is considered an important aspect of the pathomechanism of amyotrophic lateral sclerosis (ALS). However, a mechanism including the role of transactive response DNA-binding protein 43 (TDP-43) in axons… read more here.

Keywords: nerve; nerve bundles; intramuscular nerve; cohort study ... See more keywords

Optic Nerve Atrophy Conditions Associated With 3D Unsegmented Optical Coherence Tomography Volumes Using Deep Learning.

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recommendations! Published in 2025 at "JAMA ophthalmology"

DOI: 10.1001/jamaophthalmol.2025.2766

Abstract: Importance Accurate differentiation of optic nerve head (ONH) atrophy is vital for guiding diagnosis and treatment of conditions such as glaucoma, nonarteritic anterior ischemic optic neuropathy (NAION), and optic neuritis. Traditional 2-dimensional assessments may overlook… read more here.

Keywords: deep learning; naion; nerve; optic neuritis ... See more keywords

Sciatic nerve microvascular permeability in type 2 diabetes decreased in patients with neuropathy

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recommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.51563

Abstract: Clinical and histological studies have found evidence that nerve ischemia is a major contributor to diabetic neuropathy (DN) in type 2 diabetes (T2D). The aim of this study was to investigate peripheral nerve microvascular permeability… read more here.

Keywords: nerve; microvascular permeability; type diabetes; nerve microvascular ... See more keywords

Corneal confocal microscopy to detect early immune‐mediated small nerve fibre loss in AL amyloidosis

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recommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.51565

Abstract: Light chain (AL) amyloidosis is a life‐threatening disorder characterised by extracellular deposition of amyloid leading to dysfunction of multiple organs. Peripheral nerve involvement, particularly small fibre neuropathy, may be associated with poorer survival. Corneal confocal… read more here.

Keywords: small nerve; corneal confocal; microscopy; nerve ... See more keywords

A Dual‐Network Nerve Adhesive with Enhanced Adhesion Strength Promotes Transected Peripheral Nerve Repair

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recommendations! Published in 2022 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202209971

Abstract: Peripheral nerve transection has a high prevalence and results in functional loss of affected limbs. The current clinical treatment using suture anastomosis significantly limits nerve recovery due to severe inflammation, secondary damage, and fibrosis. Fibrin… read more here.

Keywords: adhesion; adhesion strength; nerve; nerve adhesive ... See more keywords

Constructing Nerve Guidance Conduit using dECM‐Doped Conductive Hydrogel to Promote Peripheral Nerve Regeneration

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recommendations! Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202402698

Abstract: Peripheral nerve injury often leads to the loss of neurological functions due to the slow regeneration rate and inefficient functional reconstruction. Current clinical treatments using nerve guidance conduits (NGCs) still face challenges in providing a… read more here.

Keywords: nerve; conduit; peripheral nerve; regeneration ... See more keywords

A Janus Mg2+ and H2 Pump Conduit for Enhanced Peripheral Nerve Regeneration

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recommendations! Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202424040

Abstract: Peripheral nerve injuries, often caused by trauma and tumor resection, severely impair motor and sensory functions. While autologous nerve grafting remains the gold standard, its efficiency is hindered by limited donor tissue availability, donor site… read more here.

Keywords: nerve; conduit; janus mg2; nerve regeneration ... See more keywords

A Self‐Curling Si 3 N 4 ‐Biofunctionalized Nerve Wrap for Suture‐Free Peripheral Nerve Repair with Multimodal Regenerative Bioregulation

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recommendations! Published in 2025 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202512462

Abstract: The treatment of peripheral nerve injury (PNI) faces dual challenges: inadequate bioactive regulation and suture‐induced inflammatory responses from mechanical stress concentration, critically impairing axonal regeneration. An integrated therapeutic system featuring a Si 3 N 4… read more here.

Keywords: nerve wrap; nerve; suture; wrap ... See more keywords

Acellular Cauda Equina Allograft as Main Material Combined with Biodegradable Chitin Conduit for Regeneration of Long‐Distance Sciatic Nerve Defect in Rats

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recommendations! Published in 2018 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.201800276

Abstract: Autologous nerve grafting (ANG), the gold standard treatment for peripheral nerve defects, still has many restrictions. In this study, the acellular cauda equina allograft (ACEA), which consists of biodegradable chitin conduit and acellular cauda equina,… read more here.

Keywords: chitin conduit; long distance; cauda equina; nerve ... See more keywords

Multifunctional Double‐Layer Composite Hydrogel Conduit Based on Chitosan for Peripheral Nerve Repairing

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recommendations! Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202200115

Abstract: Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice. Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve… read more here.

Keywords: double layer; conduit; hydrogel; peripheral nerve ... See more keywords

A Dual‐Modal Magnetic Resonance/Photoacoustic Imaging Tracer for Long‐Term High‐Precision Tracking and Facilitating Repair of Peripheral Nerve Injuries

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recommendations! Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202200183

Abstract: Neuroanatomical tracing is considered a crucial technique to assess the axonal regeneration level after injury, but traditional tracers do not meet the needs of in vivo neural tracing in deep tissues. Magnetic resonance (MR) and… read more here.

Keywords: magnetic resonance; resonance photoacoustic; dual modal; peripheral nerve ... See more keywords