TDP-43 Accumulation Within Intramuscular Nerve Bundles of Patients With Amyotrophic Lateral Sclerosis.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.1113
Abstract: Importance Degeneration of neuromuscular junctions and axons is considered an important aspect of the pathomechanism of amyotrophic lateral sclerosis (ALS). However, a mechanism including the role of transactive response DNA-binding protein 43 (TDP-43) in axons… read more here.
Keywords: nerve; nerve bundles; intramuscular nerve; cohort study ... See more keywords
Sciatic nerve microvascular permeability in type 2 diabetes decreased in patients with neuropathy
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51563
Abstract: Clinical and histological studies have found evidence that nerve ischemia is a major contributor to diabetic neuropathy (DN) in type 2 diabetes (T2D). The aim of this study was to investigate peripheral nerve microvascular permeability… read more here.
Keywords: nerve; microvascular permeability; type diabetes; nerve microvascular ... See more keywords
Corneal confocal microscopy to detect early immune‐mediated small nerve fibre loss in AL amyloidosis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51565
Abstract: Light chain (AL) amyloidosis is a life‐threatening disorder characterised by extracellular deposition of amyloid leading to dysfunction of multiple organs. Peripheral nerve involvement, particularly small fibre neuropathy, may be associated with poorer survival. Corneal confocal… read more here.
Keywords: small nerve; corneal confocal; microscopy; nerve ... See more keywords
A Dual‐Network Nerve Adhesive with Enhanced Adhesion Strength Promotes Transected Peripheral Nerve Repair
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202209971
Abstract: Peripheral nerve transection has a high prevalence and results in functional loss of affected limbs. The current clinical treatment using suture anastomosis significantly limits nerve recovery due to severe inflammation, secondary damage, and fibrosis. Fibrin… read more here.
Keywords: adhesion; adhesion strength; nerve; nerve adhesive ... See more keywords
Acellular Cauda Equina Allograft as Main Material Combined with Biodegradable Chitin Conduit for Regeneration of Long‐Distance Sciatic Nerve Defect in Rats
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201800276
Abstract: Autologous nerve grafting (ANG), the gold standard treatment for peripheral nerve defects, still has many restrictions. In this study, the acellular cauda equina allograft (ACEA), which consists of biodegradable chitin conduit and acellular cauda equina,… read more here.
Keywords: chitin conduit; long distance; cauda equina; nerve ... See more keywords
Multifunctional Double‐Layer Composite Hydrogel Conduit Based on Chitosan for Peripheral Nerve Repairing
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200115
Abstract: Peripheral nerve regeneration and functional recovery is a major challenge in clinical practice. Nerve conduit is an effective treatment for peripheral nerve repair, but the traditional hollow nerve conduit is not satisfactory in peripheral nerve… read more here.
Keywords: double layer; conduit; hydrogel; peripheral nerve ... See more keywords
A Dual‐Modal Magnetic Resonance/Photoacoustic Imaging Tracer for Long‐Term High‐Precision Tracking and Facilitating Repair of Peripheral Nerve Injuries
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200183
Abstract: Neuroanatomical tracing is considered a crucial technique to assess the axonal regeneration level after injury, but traditional tracers do not meet the needs of in vivo neural tracing in deep tissues. Magnetic resonance (MR) and… read more here.
Keywords: magnetic resonance; resonance photoacoustic; dual modal; peripheral nerve ... See more keywords
Experimental Study on Repairing Peripheral Nerve Defects with Novel Bionic Tissue Engineering.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203199
Abstract: Peripheral nerve defects are a worldwide problem, and autologous nerve transplantation is currently the gold-standard treatment for them. Tissue-engineered nerve (TEN) grafts are widely considered promising methods for the same, and have attracted much attention.… read more here.
Keywords: novel bionic; nerve defects; peripheral nerve; nerve ... See more keywords
Silk‐in‐Silk Nerve Guidance Conduits Enhance Regeneration in a Rat Sciatic Nerve Injury Model
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202203237
Abstract: Advanced nerve guidance conduits can provide an off‐the‐shelf alternative to autografts for the rehabilitation of segmental peripheral nerve injuries. In this study, the excellent processing ability of silk fibroin and the outstanding cell adhesion quality… read more here.
Keywords: rat sciatic; guidance conduits; silk; nerve ... See more keywords
4D Printed Programmable Shape-morphing Hydrogels as Intraoperative Self-folding Nerve Conduits for Sutureless Neurorrhaphy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300701
Abstract: There only a few reports of implantable 4D printed biomaterials, most of which exhibit slow deformations rendering them unsuitable for in situ surgical deployment. In this study, a hydrogel system was engineered with defined swelling… read more here.
Keywords: printed programmable; nerve; programmable shape; morphing hydrogels ... See more keywords
3D Printed Personalized Nerve Guide Conduits for Precision Repair of Peripheral Nerve Defects
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202103875
Abstract: The treatment of peripheral nerve defects has always been one of the most challenging clinical practices in neurosurgery. Currently, nerve autograft is the preferred treatment modality for peripheral nerve defects, while the therapy is constantly… read more here.
Keywords: peripheral nerve; nerve defects; nerve guide; nerve ... See more keywords