Comparative study of decellularization techniques to obtain natural extracellular matrix scaffolds of human peripheral-nerve allografts.
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DOI: 10.1007/s10561-021-09977-x
Abstract: BACKGROUND We hypothesize that adding sonication cycles to the process of decellularization of cadaveric human peripheral nerves will increase the removal of cell debris and myelin sheath, increasing their utility as allografts. METHODS Our aim… read more here.
Keywords: human peripheral; nerve allografts; decellularization; peripheral nerve ... See more keywords
Noncellular Modification of Acellular Nerve Allografts for Peripheral Nerve Reconstruction: A Systematic Critical Review of the Animal Literature.
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DOI: 10.1016/j.wneu.2018.10.195
Abstract: BACKGROUND Acellular nerve allografts (ANAs) have been established as promising alternatives to autologous nerve grafts, which represent the reference standard. Our research group recently performed a systematic review of reported cell-based-enriching methods for recellularization of… read more here.
Keywords: noncellular modification; nerve allografts; acellular nerve; nerve ... See more keywords
Local delivery of tacrolimus using electrospun poly-ϵ-caprolactone nanofibres suppresses the T-cell response to peripheral nerve allografts
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DOI: 10.1088/1741-2552/acad2a
Abstract: Objective. Repair of nerve gap injuries can be achieved through nerve autografting, but this approach is restricted by limited tissue supply and donor site morbidity. The use of living nerve allografts would provide an abundant… read more here.
Keywords: poly caprolactone; peripheral nerve; nerve; nerve allografts ... See more keywords
Comparison between direct repair and human acellular nerve allografting during contralateral C7 transfer to the upper trunk for restoration of shoulder abduction and elbow flexion
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DOI: 10.4103/1673-5374.262600
Abstract: Direct coaptation of contralateral C7 to the upper trunk could avoid the interposition of nerve grafts. We have successfully shortened the gap and graft lengths, and even achieved direct coaptation. However, direct repair can only… read more here.
Keywords: direct repair; shoulder abduction; nerve allografts; acellular nerve ... See more keywords
Functional and immunological peculiarities of peripheral nerve allografts
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DOI: 10.4103/1673-5374.322445
Abstract: This review addresses the accumulating evidence that live (not decellularized) allogeneic peripheral nerves are functionally and immunologically peculiar in comparison with many other transplanted allogeneic tissues. This is relevant because live peripheral nerve allografts are… read more here.
Keywords: functional immunological; peculiarities peripheral; immunological peculiarities; nerve allografts ... See more keywords