TDP-43 Accumulation Within Intramuscular Nerve Bundles of Patients With Amyotrophic Lateral Sclerosis.
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DOI: 10.1001/jamaneurol.2022.1113
Abstract: Importance Degeneration of neuromuscular junctions and axons is considered an important aspect of the pathomechanism of amyotrophic lateral sclerosis (ALS). However, a mechanism including the role of transactive response DNA-binding protein 43 (TDP-43) in axons… read more here.
Keywords: nerve; nerve bundles; intramuscular nerve; cohort study ... See more keywords