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Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.09.037
Abstract: Development of a functional nerve conduit to replace autografts remains a significant challenge particularly considering the compositional complexity and structural hierarchy of native peripheral nerves. In the present study, a multiscale strategy was adopted to…
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Keywords:
conduits multifunctional;
biomimetic hierarchical;
nerve conduits;
hierarchical nerve ... See more keywords
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Published in 2022 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2022.63.2.114
Abstract: Neuronal loss and axonal degeneration after spinal cord injury or peripheral injury result in the loss of sensory and motor functions. Nerve regeneration is a complicated and medical challenge that requires suitable guides to bridge…
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Keywords:
fabrication techniques;
fabrication;
nerve;
nerve conduits ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23042254
Abstract: The repair of severe nerve injuries requires an autograft or conduit to bridge the gap and avoid axon dispersion. Several conduits are used routinely, but their effectiveness is comparable to that of an autograft only…
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Keywords:
schwann cells;
nerve;
colonize nerve;
cells colonize ... See more keywords
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Published in 2019 at "Materials"
DOI: 10.3390/ma12121996
Abstract: Functionalized synthetic conduits represent a promising strategy to enhance peripheral nerve regeneration by guiding axon growth while delivering therapeutic neurotrophic factors. In this work, hollow nerve conduits made of polyvinyl alcohol partially oxidized with bromine…
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Keywords:
nerve conduits;
polyvinyl alcohol;
oxpva br2;
neurotrophic factor ... See more keywords
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Published in 2022 at "Industria Textila"
DOI: 10.35530/it.073.06.2021115
Abstract: Peripheral nerve lesions represent debilitating conditions that determine sensitive, motor and associated psychosocial losses, deeply and severely affecting the quality of life. Despite adequate microsurgical repair, functional results are variable and often dissatisfying. This study…
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Keywords:
strategies nerve;
therapeutic strategies;
nerve injuries;
nerve ... See more keywords