Mapping the N-Terminal Hexokinase-I Binding Site onto Voltage-Dependent Anion Channel-1 To Block Peripheral Nerve Demyelination.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00411
Abstract: The voltage-dependent anion channel (VDAC), the most abundant protein on the outer mitochondrial membrane, is implicated in ATP, ion and metabolite exchange with cell compartments. In particular, the VDAC participates in cytoplasmic and mitochondrial Ca2+… read more here.
Keywords: dependent anion; peripheral nerve; voltage dependent; nerve demyelination ... See more keywords
Optic nerve demyelination as the presenting feature of adrenoleukodystrophy in a child
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_2210_21
Abstract: Adrenoleukodystrophy (ALD) is an x‐linked recessive lipid storage genetic disorder due to modifications in the ABCD1 (ATP‐binding cassette) gene, resulting in defective peroxisomal β‐oxidation and the excessive collection of very‐long‐chain fatty acids (VLCFAs) in tissues… read more here.
Keywords: presenting feature; optic nerve; demyelination presenting; nerve demyelination ... See more keywords