Silk‐in‐Silk Nerve Guidance Conduits Enhance Regeneration in a Rat Sciatic Nerve Injury Model
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202203237
Abstract: Advanced nerve guidance conduits can provide an off‐the‐shelf alternative to autografts for the rehabilitation of segmental peripheral nerve injuries. In this study, the excellent processing ability of silk fibroin and the outstanding cell adhesion quality… read more here.
Keywords: rat sciatic; guidance conduits; silk; nerve ... See more keywords
Scalable Fabrication of Porous Microchannel Nerve Guidance Scaffolds with Complex Geometries.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201902021
Abstract: Microchannel scaffolds accelerate nerve repair by guiding growing neuronal processes across injury sites. Although geometry, materials chemistry, stiffness, and porosity have been shown to influence nerve growth within nerve guidance scaffolds, independent tuning of these… read more here.
Keywords: guidance scaffolds; nerve guidance; porous microchannel; fabrication ... See more keywords
3D Printed Conductive Multiscale Nerve Guidance Conduit with Hierarchical Fibers for Peripheral Nerve Regeneration
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205744
Abstract: Nerve guidance conduits (NGCs) have become a promising alternative for peripheral nerve regeneration; however, the outcome of nerve regeneration and functional recovery is greatly affected by the physical, chemical, and electrical properties of NGCs. In… read more here.
Keywords: peripheral nerve; nerve; nerve guidance; conductive multiscale ... See more keywords
Strategies for neurotrophin‐3 and chondroitinase ABC release from freeze‐cast chitosan–alginate nerve‐guidance scaffolds
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1912
Abstract: Freeze casting, or controlled unidirectional solidification, can be used to fabricate chitosan–alginate (C–A) scaffolds with highly aligned porosity that are suitable for use as nerve‐guidance channels. To augment the guidance of growth across a spinal… read more here.
Keywords: nerve guidance; neurotrophin chondroitinase; guidance; chondroitinase abc ... See more keywords
3D Gradient and Linearly Aligned Magnetic Microcapsules in Nerve Guidance Conduits with Remotely Spatiotemporally Controlled Release to Enhance Peripheral Nerve Repair.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c11362
Abstract: Although numerous strategies have been implemented to develop nerve guidance conduits (NGCs) to treat peripheral nerve injury (PNI), functionalization of an NGC to make it remotely controllable for providing spatiotemporal modulation on in situ nerve… read more here.
Keywords: guidance conduits; peripheral nerve; guidance; nerve ... See more keywords
Conductive Nerve Guidance Conduits Based on Morpho Butterfly Wings for Peripheral Nerve Repair.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c11627
Abstract: Peripheral nerve injury (PNI), causing loss of sensory and motor function, is a complex and challenging disease in the clinic due to the restricted regeneration capacity. Nerve guidance conduits (NGCs) have become a promising substitute… read more here.
Keywords: morpho butterfly; guidance conduits; peripheral nerve; nerve repair ... See more keywords
Platelet-rich fibrin membrane nerve guidance conduit: a potentially promising method for peripheral nerve injuries
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000000726
Abstract: Supplemental Digital Content is available in the text read more here.
Keywords: nerve; platelet rich; fibrin membrane; membrane nerve ... See more keywords
A printability study of multichannel nerve guidance conduits using projection-based three-dimensional printing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomaterials Applications"
DOI: 10.1177/08853282221101148
Abstract: Multichannel nerve guidance conduits (NGCs) replicating the native architecture of peripheral nerves have emerged as promising alternatives to autologous nerve grafts. However, manufacturing multichannel NGCs is challenging in terms of desired structural stability and resolution.… read more here.
Keywords: printing; guidance conduits; projection based; multichannel nerve ... See more keywords
Nanoparticles for neurotrophic factor delivery in nerve guidance conduits for peripheral nerve repair.
Sign Up to like & getrecommendations! Published in 2022 at "Nanomedicine"
DOI: 10.2217/nnm-2021-0413
Abstract: Peripheral nerve injuries are a major source of disabilities, and treatment of long nerve gap autografts is the gold standard. However, due to poor availability and donor-site morbidity, research is directed towards the development of… read more here.
Keywords: guidance conduits; peripheral nerve; nerve; nanoparticles neurotrophic ... See more keywords
Advances in Electrospun Nerve Guidance Conduits for Engineering Neural Regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14020219
Abstract: Injuries to the peripheral nervous system result in devastating consequences with loss of motor and sensory function and lifelong impairments. Current treatments have largely relied on surgical procedures, including nerve autografts to repair damaged nerves.… read more here.
Keywords: guidance conduits; nerve guidance; nerve; nerve autografts ... See more keywords
Optimization of nanofiber scaffold properties towards nerve guidance channel design
Sign Up to like & getrecommendations! Published in 2018 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.235023
Abstract: Nerve guidance channels are limited by lack of topographical guidance: Treatment of sizeable nerve gaps remains problematic following peripheral nerve injury. Functional outcomes are good when neurorrhaphy, or direct end-to-end suture repair, is possible. The… read more here.
Keywords: nanofiber scaffold; nerve guidance; guidance channels; generation ... See more keywords