Phosphorylated Upstream Frameshift 1–dependent Nonsense-mediated μ-Opioid Receptor mRNA Decay in the Spinal Cord Contributes to the Development of Neuropathic Allodynia–like Behavior in Rats
Sign Up to like & getrecommendations! Published in 2023 at "Anesthesiology"
DOI: 10.1097/aln.0000000000004550
Abstract: Background: Nonsense-mediated messenger RNA (mRNA) decay increases targeted mRNA degradation and has been implicated in the regulation of gene expression in neurons. The authors hypothesized that nonsense-mediated μ-opioid receptor mRNA decay in the spinal cord… read more here.
Keywords: nonsense mediated; nerve ligation; opioid receptor; mrna ... See more keywords
Loss of SNHG4 Attenuated Spinal Nerve Ligation-Triggered Neuropathic Pain through Sponging miR-423-5p
Sign Up to like & getrecommendations! Published in 2020 at "Mediators of Inflammation"
DOI: 10.1155/2020/2094948
Abstract: Neuropathic pain is an intractable comorbidity of spinal cord injury. Increasing noncoding RNAs have been implicated in neuropathic pain development. lncRNAs have been recognized as significant regulators of neuropathic pain. lncRNA Small Nucleolar RNA Host… read more here.
Keywords: spinal nerve; nerve ligation; mir 423; neuropathic pain ... See more keywords
Temporal Changes of Spinal Transcriptomic Profiles in Mice With Spinal Nerve Ligation
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.01357
Abstract: Neuropathic pain (NP) is an intractable disease accompanying with allodynia, hyperalgesia and spontaneous pain. Accumulating evidence suggested that large volume of neurotransmitters, genes, and signaling pathways were implicated with the initiation and development of NP,… read more here.
Keywords: spinal nerve; 28d group; group; nerve ligation ... See more keywords