A Janus Mg2+ and H2 Pump Conduit for Enhanced Peripheral Nerve Regeneration
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DOI: 10.1002/adfm.202424040
Abstract: Peripheral nerve injuries, often caused by trauma and tumor resection, severely impair motor and sensory functions. While autologous nerve grafting remains the gold standard, its efficiency is hindered by limited donor tissue availability, donor site… read more here.
Keywords: nerve; conduit; janus mg2; nerve regeneration ... See more keywords
Advances in Controlling Differentiation of Adult Stem Cells for Peripheral Nerve Regeneration
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DOI: 10.1002/adhm.201701046
Abstract: Adult stems cells, possessing the ability to grow, migrate, proliferate, and transdifferentiate into various specific phenotypes, constitute a great asset for peripheral nerve regeneration. Adult stem cells' ability to undergo transdifferentiation is sensitive to various… read more here.
Keywords: adult stem; stem; peripheral nerve; stem cells ... See more keywords
Biomechanically-adapted immunohydrogels reconstructing myelin sheath for peripheral nerve regeneration.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202201596
Abstract: Myelin sheath reconstruction plays an important role in peripheral nerve regeneration. But the hindered reconstruction of myelin sheath due to the inadequate repair phenotypes of macrophages and Schwann cells after peripheral nerve injury often causes… read more here.
Keywords: biomechanically adapted; peripheral nerve; nerve regeneration; myelin sheath ... See more keywords
Architecture‐Engineered Electrospinning Cascade Regulates Spinal Microenvironment to Promote Nerve Regeneration
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202658
Abstract: The inflammatory cascade after spinal cord injury (SCI) causes necrotizing apoptosis of local stem cells, which limits nerve regeneration. Therefore, coordinating the inflammatory immune response and neural stem cell (NSC) functions is key to promoting… read more here.
Keywords: regeneration; sci; system; microenvironment ... See more keywords
Shape‐Persistent Conductive Nerve Guidance Conduits for Peripheral Nerve Regeneration
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DOI: 10.1002/adhm.202401160
Abstract: To solve the problems of slow regeneration and mismatch of axon regeneration after peripheral nerve injury, nerve guidance conduits (NGCs) have been widely used to promote nerve regeneration. Multichannel NGCs have been widely studied to… read more here.
Keywords: nerve; persistent conductive; shape persistent; nerve regeneration ... See more keywords
Adhesive and Conductive Fibrous Hydrogel Bandages for Effective Peripheral Nerve Regeneration
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202403722
Abstract: Peripheral nerve injury is a common disease resulting in reversible and irreversible impairments of motor and sensory functions. In addition to conventional surgical interventions such as nerve grafting and neurorrhaphy, nerve guidance conduits are used… read more here.
Keywords: nerve; hydrogel; nerve regeneration; peripheral nerve ... See more keywords
MRI‐Based Evaluation Improves the Validity of Rodent Nerve Regeneration Studies
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DOI: 10.1002/adhm.202501631
Abstract: Rodent models are commonly used in preclinical studies on bioengineered conduits to induce nerve regeneration, but they often fail to predict human outcomes accurately. It is suspected that conventional evaluation methods, such as evoked electromyography… read more here.
Keywords: rodent nerve; mri based; nerve regeneration; based evaluation ... See more keywords
Modulation of the Crosstalk between Schwann Cells and Macrophages for Nerve Regeneration: A Therapeutic Strategy Based on a Multifunctional Tetrahedral Framework Nucleic Acids System
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202202513
Abstract: Peripheral nerve injury (PNI) is currently recognized as one of the most significant public health issues and affects the general well‐being of millions of individuals worldwide. Despite advances in nerve tissue engineering, nerve repair still… read more here.
Keywords: regeneration; multifunctional tetrahedral; tetrahedral framework; framework nucleic ... See more keywords
3D Printed Conductive Multiscale Nerve Guidance Conduit with Hierarchical Fibers for Peripheral Nerve Regeneration
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205744
Abstract: Nerve guidance conduits (NGCs) have become a promising alternative for peripheral nerve regeneration; however, the outcome of nerve regeneration and functional recovery is greatly affected by the physical, chemical, and electrical properties of NGCs. In… read more here.
Keywords: peripheral nerve; nerve; nerve guidance; conductive multiscale ... See more keywords
Sensation, mechanoreceptor, and nerve fiber function after nerve regeneration
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DOI: 10.1002/ana.25102
Abstract: Sensation is essential for recovery after peripheral nerve injury. However, the relationship between sensory modalities and function of regenerated fibers is uncertain. We have investigated the relationships between touch threshold, tactile gnosis, and mechanoreceptor and… read more here.
Keywords: function nerve; function; nerve; fiber function ... See more keywords
Electrical stimulation accelerates Wallerian degeneration and promotes nerve regeneration after sciatic nerve injury
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24309
Abstract: Following peripheral nerve injury (PNI), Wallerian degeneration (WD) in the distal stump can generate a microenvironment favorable for nerve regeneration. Brief low‐frequency electrical stimulation (ES) is an effective treatment for PNI, but the mechanism underlying… read more here.
Keywords: nerve injury; regeneration; degeneration; nerve regeneration ... See more keywords