Advances in Controlling Differentiation of Adult Stem Cells for Peripheral Nerve Regeneration
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201701046
Abstract: Adult stems cells, possessing the ability to grow, migrate, proliferate, and transdifferentiate into various specific phenotypes, constitute a great asset for peripheral nerve regeneration. Adult stem cells' ability to undergo transdifferentiation is sensitive to various… read more here.
Keywords: adult stem; stem; peripheral nerve; stem cells ... See more keywords
Biomechanically-adapted immunohydrogels reconstructing myelin sheath for peripheral nerve regeneration.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202201596
Abstract: Myelin sheath reconstruction plays an important role in peripheral nerve regeneration. But the hindered reconstruction of myelin sheath due to the inadequate repair phenotypes of macrophages and Schwann cells after peripheral nerve injury often causes… read more here.
Keywords: biomechanically adapted; peripheral nerve; nerve regeneration; myelin sheath ... See more keywords
Architecture‐Engineered Electrospinning Cascade Regulates Spinal Microenvironment to Promote Nerve Regeneration
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202658
Abstract: The inflammatory cascade after spinal cord injury (SCI) causes necrotizing apoptosis of local stem cells, which limits nerve regeneration. Therefore, coordinating the inflammatory immune response and neural stem cell (NSC) functions is key to promoting… read more here.
Keywords: regeneration; sci; system; microenvironment ... See more keywords
Modulation of the Crosstalk between Schwann Cells and Macrophages for Nerve Regeneration: A Therapeutic Strategy Based on a Multifunctional Tetrahedral Framework Nucleic Acids System
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202202513
Abstract: Peripheral nerve injury (PNI) is currently recognized as one of the most significant public health issues and affects the general well‐being of millions of individuals worldwide. Despite advances in nerve tissue engineering, nerve repair still… read more here.
Keywords: regeneration; multifunctional tetrahedral; tetrahedral framework; framework nucleic ... See more keywords
3D Printed Conductive Multiscale Nerve Guidance Conduit with Hierarchical Fibers for Peripheral Nerve Regeneration
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205744
Abstract: Nerve guidance conduits (NGCs) have become a promising alternative for peripheral nerve regeneration; however, the outcome of nerve regeneration and functional recovery is greatly affected by the physical, chemical, and electrical properties of NGCs. In… read more here.
Keywords: peripheral nerve; nerve; nerve guidance; conductive multiscale ... See more keywords
Sensation, mechanoreceptor, and nerve fiber function after nerve regeneration
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Neurology"
DOI: 10.1002/ana.25102
Abstract: Sensation is essential for recovery after peripheral nerve injury. However, the relationship between sensory modalities and function of regenerated fibers is uncertain. We have investigated the relationships between touch threshold, tactile gnosis, and mechanoreceptor and… read more here.
Keywords: function nerve; function; nerve; fiber function ... See more keywords
Electrical stimulation accelerates Wallerian degeneration and promotes nerve regeneration after sciatic nerve injury
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24309
Abstract: Following peripheral nerve injury (PNI), Wallerian degeneration (WD) in the distal stump can generate a microenvironment favorable for nerve regeneration. Brief low‐frequency electrical stimulation (ES) is an effective treatment for PNI, but the mechanism underlying… read more here.
Keywords: nerve injury; regeneration; degeneration; nerve regeneration ... See more keywords
GDNF‐ADSCs‐APG embedding enhances sciatic nerve regeneration after electrical injury in a rat model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28759
Abstract: The pluripotency of adipose‐derived stem cells (ADSCs) makes them appropriate for tissue repair and wound healing. Owing to the repair properties of autologous platelet–rich gel (APG), which is based on easily accessible blood platelets, its… read more here.
Keywords: adscs apg; adscs; gdnf adscs; sciatic nerve ... See more keywords
Proteomic expression profile of injured rat peripheral nerves revealed biological networks and processes associated with nerve regeneration
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26478
Abstract: Peripheral nerve regeneration is regulated through the coordinated spatio‐temporal activation of multiple cellular pathways. In this work, an integrated proteomics and bioinformatics approach was employed to identify differentially expressed proteins at the injury‐site of rat… read more here.
Keywords: expression profile; expression; proteomic expression; nerve ... See more keywords
A little trick to make inside out vein graft technique easier in experimental animal models
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DOI: 10.1002/micr.30032
Abstract: Inside out vein graft is a well described method to create, in experimental setting, a biologic conduit for nerve regeneration studies. It consists in pulling the vein through itself to invert the normal orientation and… read more here.
Keywords: vein; inside vein; vein graft; little trick ... See more keywords
Combination of BMSCs‐laden acellular nerve xenografts transplantation and G‐CSF administration promotes sciatic nerve regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Synapse"
DOI: 10.1002/syn.22093
Abstract: Peripheral nerve gaps often lead to interrupted innervation, manifesting as severe sensory and motor dysfunctions. The repairs of the nerve injuries have not achieved satisfactory curative effects in clinic. The transplantation of bone marrow stromal… read more here.
Keywords: bmscs laden; transplantation; acellular nerve; nerve ... See more keywords