Articles with "nesolicaftor" as a keyword



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The CFTR Amplifier Nesolicaftor Rescues TGF-β1 Inhibition of Modulator-Corrected F508del CFTR Function

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231810956

Abstract: Highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators have led to dramatic improvements in lung function in many people with cystic fibrosis (PwCF). However, the efficacy of CFTR modulators may be hindered by persistent… read more here.

Keywords: cftr amplifier; function; f508del cftr; cftr ... See more keywords