Abstract 137: Impact of Leptin Deficiency Compared to Neuronal Specific Leptin Receptor Deletion on Cardiometabolic Regulation
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DOI: 10.1161/hyp.74.suppl_1.137
Abstract: The main goal of this study was to compare the impact of whole-body leptin deficiency with neuronal specific leptin receptor (LR) deletion on metabolic and cardiovascular regulation. Liver fat, diacylglycerol acyltransferase-2 (DGTA2) and CD36 protein… read more here.
Keywords: nestin cre; cre mice; mice; leptin deficiency ... See more keywords
Neuronal Suppressor of Cytokine Signaling 3: Role in Modulating Chronic Metabolic and Cardiovascular Effects of Leptin
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DOI: 10.1161/hypertensionaha.118.11127
Abstract: We determined whether deficiency of neuronal SOCS3 (suppressor of cytokine signaling 3)—a potential negative regulator of leptin signaling—amplifies the chronic effects of leptin on food intake, energy expenditure, glucose, and blood pressure (BP) and protects… read more here.
Keywords: nestin cre; socs3; versus; socs3 nestin ... See more keywords