Investigation of the structure‐activity relationship in ponericin L1 from Neoponera goeldii
Sign Up to like & getrecommendations! Published in 2020 at "Peptide Science"
DOI: 10.1002/pep2.24162
Abstract: Naturally derived antimicrobial peptides have been an area of great interest because of high selectivity against bacterial targets over host cells and the limited development of bacterial resistance to these molecules throughout evolution. There are… read more here.
Keywords: investigation structure; net charge; activity; ponericin ... See more keywords
Superoxide dismutase 1 is positively selected to minimize protein aggregation in great apes
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2519-8
Abstract: Positive (adaptive) selection has recently been implied in human superoxide dismutase 1 (SOD1), a highly abundant antioxidant protein with energy signaling and antiaging functions, one of very few examples of direct selection on a human… read more here.
Keywords: protein; sod1; selection; great apes ... See more keywords
A Systematic Investigation into the Influence of Net Charge on the Biological Distribution of Radiometalated Peptides Using [68Ga]Ga-DOTA-TATE Derivatives.
Sign Up to like & getrecommendations! Published in 2023 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.3c00007
Abstract: Recently, several radiometalated peptides have been approved for clinical imaging and/or therapy (theranostics) of several types of cancer; nonetheless, the primary challenge that most of these peptides confront is significant renal uptake and retention, which… read more here.
Keywords: net charge; tate; dota tate; 68ga dota ... See more keywords
A New Split Charge Equilibration Model and REPEAT Electrostatic Potential Fitted Charges for Periodic Frameworks with a Net Charge.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.6b00998
Abstract: Periodic frameworks that possess a net charge, such as zeolites, are an important class of materials in wide use. For guest-host interactions to be simulated in these materials, partial atomic charges are often used. In… read more here.
Keywords: electrostatic potential; charge; potential fitted; model ... See more keywords
Effect of polyampholyte net charge on complex coacervation between polyampholytes and inorganic polyoxometalate giant anions.
Sign Up to like & getrecommendations! Published in 2020 at "Soft matter"
DOI: 10.1039/d0sm01565b
Abstract: The effect of net charge of zwitterionic polymers on the phase behavior and viscoelastic properties of hybrid polyampholyte-polyoxometalate (POM) complexes in salted aqueous solutions is investigated with polyampholyte copolymers consisting of both positively and negatively… read more here.
Keywords: polyoxometalate; giant; charge; effect ... See more keywords
Study of higher moments of net-charge multiplicity distributions using a multiphase transport model
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Physics C"
DOI: 10.1088/1674-1137/abfd29
Abstract: The moments and moment products of conserved charges are believed to be sensitive to the critical fluctuations, which have been used to search for the QCD critical point. Using a dynamical multiphase transport model, we… read more here.
Keywords: net charge; moment products; multiplicity distributions; charge multiplicity ... See more keywords
Low‐density lipoprotein net charge is a risk factor for atherosclerosis in lupus patients independent of lipid concentrations
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.13445
Abstract: Patients with systemic lupus erythematosus (SLE) suffer from accelerated atherosclerosis. Their most common cause of death is a cardiovascular disease (CVD), in spite of the presence of moderate lipid alterations and normal cardiovascular risk scores.… read more here.
Keywords: atherosclerosis; density lipoprotein; risk; low density ... See more keywords
Contributions of Net Charge on the PlyC Endolysin CHAP Domain
Sign Up to like & getrecommendations! Published in 2019 at "Antibiotics"
DOI: 10.3390/antibiotics8020070
Abstract: Bacteriophage endolysins, enzymes that degrade the bacterial peptidoglycan (PG), have gained an increasing interest as alternative antimicrobial agents, due to their ability to kill antibiotic resistant pathogens efficiently when applied externally as purified proteins. Typical… read more here.
Keywords: charge; chap domain; endolysin; net charge ... See more keywords