FTY720 induces neutrophil extracellular traps via a NADPH oxidase-independent pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.109015
Abstract: FTY720 is an immunosuppressive agent which has been approved to treat multiple sclerosis (MS). The main object of the present study is to investigate whether FTY720 has the potential to induce the formation of neutrophil… read more here.
Keywords: neutrophil extracellular; fty720; formation; nadph oxidase ... See more keywords
Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.119836
Abstract: Neutrophil elastase (NE) is a serine protease stored in the azurophilic granules of neutrophils and released into the extracellular milieu during inflammatory response or formation of neutrophil extracellular traps (NETs). Neutrophils release NETs to entrap… read more here.
Keywords: neutrophil extracellular; formation; neutrophil elastase; endotoxic shock ... See more keywords
Substrate stiffness induces neutrophil extracellular trap (NET) formation through focal adhesion kinase activation.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.120715
Abstract: Neutrophils predominate the early inflammatory response to tissue injury and implantation of biomaterials. Recent studies have shown that neutrophil activation can be regulated by mechanical cues such as stiffness or surface wettability; however, it is… read more here.
Keywords: neutrophil extracellular; substrate stiffness; formation; activation ... See more keywords
Mitochondria-derived ATP participates in the formation of neutrophil extracellular traps induced by platelet-activating factor through purinergic signaling in cows.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2020.103768
Abstract: Neutrophil extracellular traps (NET) formation eliminates/prevents the spread of infectious agents. Platelet activating factor (PAF) is involved in infectious diseases of cattle because it recruits and activates neutrophils. However, its ability to induce NET formation… read more here.
Keywords: neutrophil extracellular; platelet activating; extracellular traps; net formation ... See more keywords
Exploring strategies and dynamic capabilities for net formation and management.
Sign Up to like & getrecommendations! Published in 2017 at "Industrial Marketing Management"
DOI: 10.1016/j.indmarman.2017.09.023
Abstract: Abstract Nets represent forms of inter-organizational collaboration in networks in which actors can pursue complex objectives beyond their individual resources or abilities. Firms seeking to effectively form and manage nets face challenges in understanding how… read more here.
Keywords: formation management; dynamic capabilities; management; management exploring ... See more keywords
Protective effect of ethyl pyruvate on gut barrier function through regulations of ROS-related NETs formation during sepsis.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular immunology"
DOI: 10.1016/j.molimm.2021.01.012
Abstract: BACKGROUND Sepsis impairs the function of the intestinal barrier through neutrophil extracellular traps (NETs). Reactive oxygen species (ROS)-induced activation of mitogen-activated protein kinase (MAPK) is involved in NET formation. Ethyl pyruvate (EP), a potent and… read more here.
Keywords: sepsis; barrier; ethyl pyruvate; formation sepsis ... See more keywords
Bongkrekic acid induced neutrophil extracellular traps via p38, ERK, PAD4, and P2X1-mediated signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2021.115580
Abstract: Bongkrekic acid (BKA) produced by pseudomonas cocovenenans is a deadly toxin, and is mainly found in spoiled or fermented foods. However, less is known on its immunotoxicity. Neutrophil extracellular traps (NETs) are a novel effector… read more here.
Keywords: neutrophil extracellular; bongkrekic acid; bka triggered; formation ... See more keywords
Fumonisin B1 triggers the formation of bovine neutrophil extracellular traps.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2020.07.006
Abstract: Fumonisin B1 (FB1) is a congener of fumonisins produced by Fusarium species that may be found as corn contaminants threatening health of humans and animals. FB1 causes a variety of toxicity effects, including hepatotoxic, nephrotoxic… read more here.
Keywords: neutrophil extracellular; fb1 immunotoxicity; extracellular traps; net formation ... See more keywords
Polychlorinated Biphenyl Quinone Metabolites Cause Neutrophil Extracellular Traps in Mouse Bone Marrow Neutrophils.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.1c00375
Abstract: Polychlorinated biphenyls (PCBs) are a group of persistent organic environmental pollutants with various toxic effects. Our previous research found that a highly reactive quinone metabolite of PCBs, namely, PCB29-pQ, causes excessive reactive oxygen species (ROS)… read more here.
Keywords: net formation; microscopy; neutrophil extracellular; extracellular traps ... See more keywords
Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-020-0381-3
Abstract: Excessive release of neutrophil extracellular traps (NETs) is associated with disease severity and contributes to tissue injury, followed by severe organ damage. Pharmacological or genetic inhibition of NET release reduces pathology in multiple inflammatory disease… read more here.
Keywords: disease; pathology; net release; mediated inflammatory ... See more keywords
NET formation differs in SLE and vasculitis
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-019-0284-9
Abstract: Sera from patients with either systemic lupus erythematosus (SLE) or antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) induce distinct forms of neutrophil extracellular trap (NET) formation, according to a new study. In an ex vivo comparison,… read more here.
Keywords: formation differs; sle vasculitis; formation; differs sle ... See more keywords