Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion
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DOI: 10.1093/cvr/cvac189
Abstract: Abstract Aims Neutrophil extracellular trap formation (NETosis) increases atherosclerotic plaque vulnerability and athero-thrombosis. However, mechanisms promoting NETosis during atherogenesis are poorly understood. We have shown that cholesterol accumulation due to myeloid cell deficiency of the… read more here.
Keywords: netosis; cholesterol accumulation; netosis atherosclerotic; atherosclerotic plaques ... See more keywords