Neutrophil Activation and Netosis Are the Key Drivers of Thrombosis in Heparin-Induced Thrombocytopenia
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-116421
Abstract: Adverse drug effects are common in clinical practice and often have a negative impact on patient safety. Heparin and heparin-derived drugs may induce an immune reaction, termed heparin-induced thrombocytopenia (HIT). HIT is mediated by IgG… read more here.
Keywords: heparin; figure; netosis; nets formation ... See more keywords
Neutrophil extracellular traps are downregulated by glucocorticosteroids in lungs in an equine model of asthma
Sign Up to like & getrecommendations! Published in 2017 at "Respiratory Research"
DOI: 10.1186/s12931-017-0689-4
Abstract: BackgroundSevere neutrophilic asthma is poorly responsive to glucocorticosteroids (GC). Neutrophil extracellular traps (NETs) within the lungs have been associated with the severity of airway obstruction and inflammation in asthma, and were found to be unaffected… read more here.
Keywords: neutrophil extracellular; nets formation; traps downregulated; asthma ... See more keywords
IgD enhances the release of neutrophil extracellular traps (NETs) via FcδR in rheumatoid arthritis patients.
Sign Up to like & getrecommendations! Published in 2022 at "International immunopharmacology"
DOI: 10.22541/au.164408019.96969408/v1
Abstract: Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disorder affecting primarily the joints. Neutrophils and the release of neutrophil extracellular traps (NETs) contribute to the pathogenesis of RA. However, IgD, which was abnormally higher in… read more here.
Keywords: nets formation; release neutrophil; rheumatoid arthritis; igd ... See more keywords
Dexamethasone Inhibits S. aureus-Induced Neutrophil Extracellular Pathogen-Killing Mechanism, Possibly through Toll-Like Receptor Regulation
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DOI: 10.3389/fimmu.2017.00060
Abstract: Neutrophils release neutrophil extracellular traps (NETs) in a pathogen-killing process called NETosis. Excessive NETs formation, however, is implicated in disease pathogenesis. Therefore, to understand how NETosis is regulated, we examined the effect of dexamethasone (DXM),… read more here.
Keywords: neutrophil extracellular; netosis; nets formation; aureus induced ... See more keywords
Differences and similarities in the phenomenon of NETs formation in oral inflammation and in oral squamous cell carcinoma
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DOI: 10.7150/jca.24238
Abstract: Taking into account the previously reported relationship between inflammation and carcinogenesis, and the scant amount of data concerning the role of neutrophil extracellular traps (NETs) in carcinogenesis, we decided to study the process of extracellular… read more here.
Keywords: cell carcinoma; oral squamous; squamous cell; inflammation ... See more keywords