Network pharmacology and molecular docking analysis on the mechanism of Cordyceps militaris polysaccharide regulating immunity through TLR4/TNF-α pathwayss.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23345
Abstract: The role of polysaccharide components in the immune system, especially immunomodulatory effects, has received increasing attention. In this context, in this study, network pharmacology was adopted to explore the hypothesis of a multitarget mechanism for… read more here.
Keywords: molecular docking; pharmacology; mechanism; network pharmacology ... See more keywords
Application prospect of traditional Chinese medicine network pharmacology in food science research.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12541
Abstract: In-depth research on the mechanism of food nutrition and bioactivity has always been a shortcoming. The main function of the food itself is to meet the nutritional needs of the human body, not the therapeutic… read more here.
Keywords: pharmacology; food; network pharmacology; medicine ... See more keywords
Systematically characterize the absorbed components of Ligustri Lucidi Fructus and their metabolic pathways in rat plasma by ultra-high-performance liquid chromatography-Q-Exactive Orbitrap tandem mass spectrometry combined with network pharmacology.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202100484
Abstract: Ligustri Lucidi Fructus is dried and mature fruit of Ligubtrum lucidum Ait., which has the effects of nourishing liver and kidney. Herein, an accurate and sensitive method was established for separation and identification of the… read more here.
Keywords: pharmacology; network pharmacology; ligustri lucidi; lucidi fructus ... See more keywords
An integrated approach of HPLC-MS-based chemical profiling, network pharmacology, and molecular docking to reveal the potential mechanisms of Qishen Gubiao Granules for treating COVID-19.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of separation science"
DOI: 10.1002/jssc.202200953
Abstract: Qishen Gubiao Granules, a traditional Chinese medicine preparation composed of 9 herbs, have been widely used to prevent and treat COVID-19 with good clinical efficacy. In the present study, an integrated strategy based on chemical… read more here.
Keywords: molecular docking; qishen gubiao; pharmacology; gubiao granules ... See more keywords
Unveiling the effect of Withania somnifera on neuronal cytoarchitecture and synaptogenesis: A combined in vitro and network pharmacology approach
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7466
Abstract: Withania somnifera (WS), is known for its remarkable contribution in herbal medicine and Ayurveda, which is therapeutically applied to improve memory and anxiety in patients. However, the pharmacological details of this plant on memory boosting… read more here.
Keywords: pharmacology; withania somnifera; network; network pharmacology ... See more keywords
Interaction between piperine and genes associated with sciatica and its mechanism based on molecular docking technology and network pharmacology
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Diversity"
DOI: 10.1007/s11030-020-10055-9
Abstract: Abstract Piperine is the main active component of Piper longum L., which is also the main component of anti-sciatica Mongolian medicine Naru Sanwei pill. It has many pharmacological activities such as anti-inflammatory and immune regulation.… read more here.
Keywords: piper longum; sciatica; pharmacology; piperine ... See more keywords
The hepatoprotective efficacy and biological mechanisms of three phenylethanoid glycosides from cistanches herba and their metabolites based on intestinal bacteria and network pharmacology.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of natural medicines"
DOI: 10.1007/s11418-021-01508-y
Abstract: Echinacoside (ECH), acteoside (ACT), and isoacteoside (ISAT), the typical phenylethanoid glycosides (PhGs) in cistanches herba, have various pharmacological activities. However, the ECH, ACT and ISAT have extremely low oral bioavailability, which is related to their… read more here.
Keywords: cistanches herba; pharmacology; network pharmacology; intestinal bacteria ... See more keywords
iTRAQ-Based Quantitative Proteomics and Network Pharmacology Revealing Hemostatic Mechanism Mediated by Zingiberis Rhizome Carbonisata in Deficiency-cold and Hemorrhagic Syndrome Rat Models.
Sign Up to like & getrecommendations! Published in 2021 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2021.109465
Abstract: Zingiberis Rhizome Carbonisata (ZRC) has been used as a hemostatic agent in traditional Chinese medicine (TCM). However, the underlying molecular mechanism remains unclear. In this study, network pharmacology method was used to predict the potential… read more here.
Keywords: mechanism; zingiberis rhizome; pharmacology; network pharmacology ... See more keywords
Exploring the mechanism of action Xianlingubao Prescription in the treatment of osteoporosis by network pharmacology
Sign Up to like & getrecommendations! Published in 2020 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2020.107240
Abstract: In this study, the network pharmacology analysis method was used to explore the bioactive components and targets of Xianlinggubao (XLGB) and further elucidate its potential biological mechanisms of action in the treatment of osteoporosis (OP).… read more here.
Keywords: medicine; pharmacology; treatment osteoporosis; network pharmacology ... See more keywords
The anti-inflammatory mechanism of the medicinal fungus puffball analysis based on network pharmacology
Sign Up to like & getrecommendations! Published in 2021 at "Informatics in Medicine Unlocked"
DOI: 10.1016/j.imu.2021.100549
Abstract: Abstract Background Puffball is a common Chinese medicine of edible and medicinal fungus. It promotes hemostasis and muscle regeneration. Recent studies have shown that puffball has a limiting effect on pain and inflammation, but the… read more here.
Keywords: medicine; anti inflammatory; network pharmacology; mechanism ... See more keywords
Therapeutic targets of vitamin C on liver injury and associated biological mechanisms: A study of network pharmacology☆
Sign Up to like & getrecommendations! Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.11.048
Abstract: &NA; In our previous studies, vitamin C (VC) exerts potent pharmacological activities against liver injury (LI). Therefore, this report was designed to use network pharmacology‐based strategy to predict therapeutic targets of VC against LI, and… read more here.
Keywords: therapeutic targets; pharmacology; network pharmacology; liver injury ... See more keywords