Transplantation of Pre‐Differentiated 3D Neural Spheroids in Decellularized Extracellular Matrix Microgels Promotes Neuronal Network Reconstruction and Functional Recovery after Severe Spinal Cord Contusion
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202407097
Abstract: Traumatic spinal cord injury (SCI) causes massive death of neurons in the spinal cords and almost complete neurological dysfunctions. Transplantation of neural stem/progenitor cells (NSPCs) is acknowledged as one of the viable SCI treatments for… read more here.
Keywords: cord; network reconstruction; spinal cord; neural spheroids ... See more keywords
Reconstructing distant interactions of multiple paths between perceptible nodes in dark networks.
Sign Up to like & getrecommendations! Published in 2022 at "Physical review. E"
DOI: 10.1103/physreve.106.014302
Abstract: Quantitative research of interdisciplinary fields, including biological and social systems, has attracted great attention in recent years. Complex networks are popular and important tools for the investigations. Explosively increasing data are created by practical networks,… read more here.
Keywords: network; multiple paths; network reconstruction; distant interactions ... See more keywords
Protein Function Prediction Based on PPI Networks: Network Reconstruction vs Edge Enrichment
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.758131
Abstract: Over the past decades, massive amounts of protein-protein interaction (PPI) data have been accumulated due to the advancement of high-throughput technologies, and but data quality issues (noise or incompleteness) of PPI have been still affecting… read more here.
Keywords: network reconstruction; edge enrichment; ppi;
Metabolic network reconstruction of Euglena gracilis: Current state, challenges, and applications
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1143770
Abstract: A metabolic model, representing all biochemical reactions in a cell, is a prerequisite for several approaches in systems biology used to explore the metabolic phenotype of an organism. Despite the use of Euglena in diverse… read more here.
Keywords: metabolic network; network; network reconstruction; euglena ... See more keywords
Performance Assessment of the Network Reconstruction Approaches on Various Interactomes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.666705
Abstract: Beyond the list of molecules, there is a necessity to collectively consider multiple sets of omic data and to reconstruct the connections between the molecules. Especially, pathway reconstruction is crucial to understanding disease biology because… read more here.
Keywords: reconstruction; reconstruction approaches; performance assessment; network reconstruction ... See more keywords