Rewiring the Epigenetic Networks in MLL-Rearranged Leukemias: Epigenetic Dysregulation and Pharmacological Interventions
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DOI: 10.3389/fcell.2019.00081
Abstract: Leukemias driven by chromosomal translocation of the mixed-lineage leukemia gene (MLL or KMT2A) are highly prevalent in pediatric oncology. The poor survival rate and lack of an effective targeted therapy for patients with MLL-rearranged (MLL-r)… read more here.
Keywords: networks mll; leukemias epigenetic; epigenetic networks; rewiring epigenetic ... See more keywords