Modeling Gene Networks to Understand Multistability in Stem Cells.
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DOI: 10.1007/978-1-4939-9224-9_8
Abstract: Stem cells are unique in their ability to differentiate into diverse phenotypes capable of displaying radically different, yet stable, gene expression profiles. Understanding this multistable behavior is key to rationally influencing stem cell differentiation for… read more here.
Keywords: modeling gene; gene networks; networks understand; stem ... See more keywords
Using microRNA Networks to Understand Cancer
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DOI: 10.3390/ijms19071871
Abstract: Human cancers are characterized by deregulated expression of multiple microRNAs (miRNAs), involved in essential pathways that confer the malignant cells their tumorigenic potential. Each miRNA can regulate hundreds of messenger RNAs (mRNAs), while various miRNAs… read more here.
Keywords: networks understand; mirna; microrna networks; using microrna ... See more keywords