212Pb-conjugated anti-rat HER2/neu antibody against a neu-N derived murine mammary carcinoma cell line: cell kill and RBE in vitro.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of radiation biology"
DOI: 10.1080/09553002.2022.2033341
Abstract: Purpose In the current work, the RBE of a 212Pb conjugated anti-HER2/neu antibody construct has been evaluated, in vitro, by colony formation assay. The RBE was estimated by comparing two absorbed dose-survival curves: the first… read more here.
Keywords: neu antibody; her2 neu; antibody; 212pb conjugated ... See more keywords
A PI3K p110α-selective inhibitor enhances the efficacy of anti-HER2/neu antibody therapy against breast cancer in mice
Sign Up to like & getrecommendations! Published in 2018 at "OncoImmunology"
DOI: 10.1080/2162402x.2017.1421890
Abstract: ABSTRACT Combination therapies with phosphoinositide 3-kinase (PI3K) inhibitors and trastuzumab (anti-human epidermal growth factor receptor [HER]2/neu antibody) are effective against HER2+ breast cancer. Isoform-selective PI3K inhibitors elicit anti-tumor immune responses that are distinct from those… read more here.
Keywords: inhibitor; antibody; neu antibody; breast cancer ... See more keywords