Neu‐P11, a novel MT1/MT2 agonist, reverses diabetes by suppressing the hypothalamic‐pituitary‐adrenal axis in rats
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DOI: 10.1016/j.ejphar.2017.07.001
Abstract: &NA; Excessive glucocorticoid (GC) in type 2 diabetes mellitus (T2DM) reduces insulin sensitivity, impairs &bgr;‐cell function, increases gluconeogenesis and glycogenolysis, impairs glucose uptake and metabolism, and reduces the insulinotropic effects of glucagon‐like peptide 1. Melatonin,… read more here.
Keywords: mt1 mt2; neu p11; p11; axis ... See more keywords