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Neu1 Is Released From Activated Microglia, Stimulating Microglial Phagocytosis and Sensitizing Neurons to Glutamate

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Published in 2022 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2022.917884

Abstract: Neuraminidase 1 (Neu1) hydrolyses terminal sialic acid residues from glycoproteins and glycolipids, and is normally located in lysosomes, but can be released onto the surface of activated myeloid cells and microglia. We report that endotoxin/lipopolysaccharide-activated… read more here.

Keywords: neuronal death; phagocytosis; microglial phagocytosis; activated microglia ... See more keywords