Mechanical Response of Neural Cells to Physiologically Relevant Stiffness Gradients
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201901036
Abstract: Abstract Understanding the influence of the mechanical environment on neurite behavior is crucial in the development of peripheral nerve repair solutions, and could help tissue engineers to direct and guide regeneration. In this study, a… read more here.
Keywords: response neural; stiffness; mechanical response; physiologically relevant ... See more keywords
A Subtractive FACS Method for Isolation of Planarian Stem Cells and Neural Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7802-1_19
Abstract: Planarians are among the metazoan organisms with the greatest regenerative abilities. This ability is based on their pluripotent stem cells, called neoblasts, which constitute 10-20% of the cells in their body. Elucidating the molecular mechanisms… read more here.
Keywords: biology; isolation planarian; planarian stem; stem cells ... See more keywords
Microglia: The Neural Cells of Nonneural Origin.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9658-2_1
Abstract: Microglia are neural cells of nonneural origin; they originate from fetal macrophages that invade neural tube early in embryogenesis and undergo the most idiosyncratic metamorphosis which coverts them into elements of neural circuitry. Microglia appeared… read more here.
Keywords: microglia neural; nonneural origin; biology; neural cells ... See more keywords
Combining Patient-Reprogrammed Neural Cells and Proteomics as a Model to Study Psychiatric Disorders.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-52479-5_26
Abstract: The mechanisms underlying the pathophysiology of psychiatric disorders are still poorly known. Most of the studies about these disorders have been conducted on postmortem tissue or in limited preclinical models. The development of human induced… read more here.
Keywords: psychiatric disorders; combining patient; study; reprogrammed neural ... See more keywords
How to Study the Uptake and Toxicity of Nanoparticles in Cultured Brain Cells: The Dos and Don’t Forgets
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2598-4
Abstract: Due to their exciting properties, engineered nanoparticles have obtained substantial attention over the last two decades. As many types of nanoparticles are already used for technical and biomedical applications, the chances that cells in the… read more here.
Keywords: uptake toxicity; study uptake; nanoparticles cultured; brain ... See more keywords
Generation of neural cells using iPSCs from sleep bruxism patients with 5-HT2A polymorphism.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of prosthodontic research"
DOI: 10.1016/j.jpor.2016.11.003
Abstract: PURPOSE Sleep bruxism (SB) is classified as a sleep-related movement disorder characterized by grinding and clenching of the teeth during sleep, which is responsible for a variety of clinical problems such as abnormal tooth attrition… read more here.
Keywords: etiology; cells using; sleep bruxism; neural cells ... See more keywords
Modeling CLN6 with IPSC-derived neural cells
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics and Metabolism"
DOI: 10.1016/j.ymgme.2018.12.299
Abstract: Neuronal ceroid lipofuscionosis type 6 (CLN6) is a neurodegenerative disease associated with dementia, seizures, and retinopathy. The disorder is due to mutations in the CLN6 gene encoding a resident ER transmembrane protein of unknown function. Similar to… read more here.
Keywords: ipsc derived; cln6; neural cells; subc puncta ... See more keywords
Cellular and Molecular Processes Are Differently Influenced in Primary Neural Cells by Slight Changes in the Physicochemical Properties of Multicore Magnetic Nanoparticles
Sign Up to like & getrecommendations! Published in 2023 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.3c02729
Abstract: Herein, we use two exemplary superparamagnetic iron oxide multicore nanoparticles (SPIONs) to illustrate the significant influence of slightly different physicochemical properties on the cellular and molecular processes that define SPION interplay with primary neural cells.… read more here.
Keywords: primary neural; cell; molecular processes; neural cells ... See more keywords
Exploration of the Effects of Substrate Stiffness on Biological Responses of Neural Cells and Their Mechanisms
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c04279
Abstract: Substrate stiffness, as a critical mechanical factor, has been proven to be an important regulator of biological responses, cellular functions, and disease occurrence. However, the effects of substrate stiffness on the phenotypes and drug responses… read more here.
Keywords: substrate stiffness; drug; responses neural; biological responses ... See more keywords
Zika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-12408-x
Abstract: Zika virus (ZIKV) invades and persists in the central nervous system (CNS), causing severe neurological diseases. However the virus journey, from the bloodstream to tissues through a mature endothelium, remains unclear. Here, we show that… read more here.
Keywords: dissemination neural; zika virus; viral dissemination; virus ... See more keywords
Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-022-28107-z
Abstract: Chromatin regulation is a key process in development but its contribution to the evolution of animals is largely unexplored. Chromatin is regulated by a diverse set of proteins, which themselves are tightly regulated in a… read more here.
Keywords: chromatin; neural cells; demethylase lsd1; nematostella vectensis ... See more keywords