Exosomes regulate neurogenesis and circuit assembly
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1902513116
Abstract: Significance Exosomes have been implicated in intercellular communication in cancer and neurodegenerative disorders. We explored their function in brain development. Proteomic analysis demonstrated that exosomes from isogenic control cultures contain neurodevelopmental signaling proteins, which are… read more here.
Keywords: neurogenesis; circuit; exosomes regulate; neural cultures ... See more keywords
Extracellular Vesicles Derived from Young Neural Cultures Attenuate Astrocytic Reactivity In Vitro
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031371
Abstract: Extracellular vesicles (EVs) play an important role in intercellular communication and are involved in both physiological and pathological processes. In the central nervous system (CNS), EVs secreted from different brain cell types exert a sundry… read more here.
Keywords: vesicles derived; neural cultures; derived young; extracellular vesicles ... See more keywords
Modelling Lyssavirus Infections in Human Stem Cell-Derived Neural Cultures
Sign Up to like & getrecommendations! Published in 2020 at "Viruses"
DOI: 10.3390/v12040359
Abstract: Rabies is a zoonotic neurological infection caused by lyssavirus that continues to result in devastating loss of human life. Many aspects of rabies pathogenesis in human neurons are not well understood. Lack of appropriate ex-vivo… read more here.
Keywords: stem cell; human stem; cell derived; neural cultures ... See more keywords