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Published in 2017 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22517
Abstract: The vertebrate central nervous system (CNS) is comprised of vast number of distinct cell types arranged in a highly organized manner. This high degree of complexity is achieved by cellular communication, including direct cell‐cell contact,…
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Keywords:
vertebrate neural;
wnt catenin;
neural development;
cell ... See more keywords
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Published in 2020 at "Human Mutation"
DOI: 10.1002/humu.23969
Abstract: DNA damage response (DDR) genes orchestrating the network of DNA repair, cell cycle control, are essential for the rapid proliferation of neural progenitor cells. To date, the potential association between specific DDR genes and the…
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Keywords:
rad9b;
loss rad9b;
neural development;
risk human ... See more keywords
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Published in 2018 at "Environmental pollution"
DOI: 10.1016/j.envpol.2017.12.110
Abstract: Triclosan (TCS) is an organic compound with a wide range of antibiotic activity and has been widely used in items ranging from hygiene products to cosmetics; however, recent studies suggest that it has several adverse…
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Keywords:
affects axon;
triclosan affects;
neural development;
zebrafish embryos ... See more keywords
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Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.035
Abstract: Background Left-right asymmetry is a fundamental organizing feature of the human brain, and neuro-psychiatric disorders such as schizophrenia sometimes involve alterations of brain asymmetry. As early as 8 weeks post conception, the majority of human…
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Keywords:
left right;
right asymmetry;
neural development;
spinal cord ... See more keywords
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Published in 2018 at "iScience"
DOI: 10.1016/j.isci.2018.09.017
Abstract: Constructing a functioning nervous system requires the precise orchestration of a vast array of mechanical, molecular, and neural-activity-dependent cues. Theoretical models can play a vital role in helping to frame quantitative issues, reveal mathematical commonalities…
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Keywords:
theoretical models;
models neural;
neural development;
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Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.01.009
Abstract: The Fezzin family member Nedd4-binding protein 3 (N4BP3) is known to regulate axonal and dendritic branching. Here, we show that n4bp3 is expressed in the neural tissue of the early Xenopus laevis embryo including the…
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Keywords:
anterior neural;
xenopus laevis;
neural development;
nedd4 binding ... See more keywords
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Published in 2017 at "Nature Reviews Neuroscience"
DOI: 10.1038/nrn.2016.185
Abstract: The stage-specific regulation of sets of enhancers by the 'programming' transcription factor islet 1 regulates the transcription of effector genes during motor neuron differentiation.
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Keywords:
control neuronal;
neuronal identity;
neural development;
relaying control ... See more keywords
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Published in 2018 at "Nature Reviews Neuroscience"
DOI: 10.1038/s41583-018-0079-z
Abstract: Steady-state RNA levels are controlled by the balance between RNA synthesis and RNA turnover. A selective RNA turnover mechanism that has received recent attention in neurons is nonsense-mediated RNA decay (NMD). NMD has been shown to…
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Keywords:
neural development;
rna decay;
nonsense mediated;
mediated rna ... See more keywords
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Published in 2023 at "Biochemical Society transactions"
DOI: 10.1042/bst20220920
Abstract: Mutations in the polyglutamine tract-binding protein 1 (PQBP1) gene are associated with Renpenning syndrome, which is characterized by microcephaly, intellectual deficiency, short stature, small testes, and distinct facial dysmorphism. Studies using different models have revealed…
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Keywords:
neural development;
function;
role pqbp1;
pqbp1 neural ... See more keywords
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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2208772119
Abstract: Significance Trabecular (spongy) bone can dynamically change its structure in response to its mechanical environment during ontogeny. In paleoanthropology, trabecular bone is used to reconstruct the locomotor behavior of extinct hominins. We show that trabecular…
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Keywords:
neural development;
development;
bone;
trabecular bone ... See more keywords
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Published in 2022 at "Fly"
DOI: 10.1080/19336934.2021.1953363
Abstract: ABSTRACT Notch signalling is a well-conserved signalling pathway that regulates cell fate through cell-cell communication. A typical feature of Notch signalling is ‘lateral inhibition’, whereby two neighbouring cells of equivalent state of differentiation acquire different…
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Keywords:
neural development;
notch dynamics;
notch;
dynamics drosophila ... See more keywords