Regulation of Neural Differentiation of ADMSCs using Graphene‐Mediated Wireless‐Localized Electrical Signals Driven by Electromagnetic Induction
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202104424
Abstract: Although adipose‐derived mesenchymal stem cells (ADMSCs) isolated from patients’ fat are considered as the most important autologous stem cells for tissue repair, significant difficulties in the neural differentiation of ADMSCs still impede stem cell therapy… read more here.
Keywords: stem; using graphene; neural differentiation; differentiation admscs ... See more keywords
Three-Dimensional Laminin Mimetic Peptide Nanofiber Gels for In Vitro Neural Differentiation.
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology journal"
DOI: 10.1002/biot.201700080
Abstract: The extracellular matrix (ECM) provides biochemical signals and structural support for cells, and its functional imitation is a fundamental aspect of biomaterial design for regenerative medicine applications. The stimulation of neural differentiation by a laminin… read more here.
Keywords: three dimensional; neural differentiation; laminin mimetic; dimensional laminin ... See more keywords
HSPGs glypican‐1 and glypican‐4 are human neuronal proteins characteristic of different neural phenotypes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24666
Abstract: Generating neurons from human stem cells has potential for brain damage therapy and neurogenesis modeling, but current efficacy is limited by culture heterogeneity and the lack of markers. We have previously reported the heparan sulfate… read more here.
Keywords: neural differentiation; gpc1 gpc4; differentiation; hspgs glypican ... See more keywords
Bezafibrate Upregulates Mitochondrial Biogenesis and Influence Neural Differentiation of Human-Induced Pluripotent Stem Cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1368-2
Abstract: Bezafibrate (BZ) regulates mitochondrial biogenesis by activation of PPAR’s receptors and enhancing the level of PGC-1α coactivator. In this report, we investigated the effect of BZ on the expression of genes (1) that are linked… read more here.
Keywords: neural differentiation; mitochondrial biogenesis; stem cells; stage ... See more keywords
Development of membrane ion channels during neural differentiation from human embryonic stem cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.07.068
Abstract: OBJECTIVE For human embryonic stem cells (hESCs) to differentiate into neurons, enormous changes has to occur leading to trigger action potential and neurotransmitter release. We attempt to determine the changes in expression of voltage gated… read more here.
Keywords: neural differentiation; differentiation; embryonic stem; stem cells ... See more keywords
Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107715
Abstract: Previous studies have suggested that the loss of the translation initiation factor eIF4G1 homolog NAT1 induces excessive self-renewability of naive pluripotent stem cells (PSCs); yet the role of NAT1 in the self-renewal and differentiation of… read more here.
Keywords: neural differentiation; differentiation; pluripotent stem; stem cells ... See more keywords
Variable Outcomes in Neural Differentiation of Human PSCs Arise from Intrinsic Differences in Developmental Signaling Pathways
Sign Up to like & getrecommendations! Published in 2020 at "Cell Reports"
DOI: 10.1016/j.celrep.2020.107732
Abstract: Summary Directed differentiation of human pluripotent stem cells varies in specificity and efficiency. Stochastic, genetic, intracellular, and environmental factors affect maintenance of pluripotency and differentiation into early embryonic lineages. However, factors affecting variation in in… read more here.
Keywords: neural differentiation; variable outcomes; differentiation human; outcomes neural ... See more keywords
Neural differentiation of mouse induced pluripotent stem cells using cadherin gene-engineered PA6 feeder cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2018.10.009
Abstract: Investigating neural differentiation of pluripotent stem cells, including induced pluripotent stem (iPS) cells, is of importance for studying early neural development and providing a potential source of cells for nerve regeneration. Stromal cell-derived inducing activity… read more here.
Keywords: cadherin gene; neural differentiation; gene engineered; feeder cells ... See more keywords
Ultra-structural morphology analysis of human cranial bone marrow mesenchymal stromal cells during neural differentiation
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2021.136179
Abstract: Neural differentiation of mesenchymal stromal cells has been widely studied. However, a comparative characterization of ultrastructural changes during neural differentiation has not been performed. In this study, we conducted scanning electron microscopy and transmission electron… read more here.
Keywords: neural differentiation; mesenchymal stromal; microscopy; stromal cells ... See more keywords
Perfluorinated Iodine Alkanes Promoted Neural Differentiation of mESCs by Targeting miRNA-34a-5p in Notch-Hes Signaling.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c01051
Abstract: The neurodevelopmental process is highly vulnerable to environmental stress from exposure to endocrine-disrupting chemicals. Perfluorinated iodine alkanes (PFIs) possess estrogenic activities, while their potential neurodevelopmental toxicity remains blurry. In the present study, the effects of… read more here.
Keywords: perfluorinated iodine; neural differentiation; iodine alkanes; differentiation ... See more keywords
Improved neural differentiation of stem cells mediated by magnetic nanoparticle-based biophysical stimulation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Chemistry B"
DOI: 10.1039/c9tb00678h
Abstract: Stem cell therapy shows great potential in the treatment of neurodegenerative diseases, in which efficient neural differentiation of stem cells is still challenging. read more here.
Keywords: neural differentiation; improved neural; differentiation stem; stem cells ... See more keywords