Human neural tube morphogenesis in vitro by geometric constraints.
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-04026-9
Abstract: Understanding human organ formation is a scientific challenge with far-reaching medical implications1,2. Three-dimensional stem-cell cultures have provided insights into human cell differentiation3,4. However, current approaches use scaffold-free stem-cell aggregates, which develop non-reproducible tissue shapes and… read more here.
Keywords: tube; neural ectoderm; human neural; neural tube ... See more keywords