Toward the next generation of vascularized human neural organoids
Sign Up to like & getrecommendations! Published in 2022 at "Medicinal Research Reviews"
DOI: 10.1002/med.21922
Abstract: Thanks to progress in the development of three‐dimensional (3D) culture technologies, human central nervous system (CNS) development and diseases have been gradually deciphered by using organoids derived from human embryonic stem cells (hESCs) or human… read more here.
Keywords: neural organoids; toward next; vascularized human; next generation ... See more keywords
Three-Dimensional Microfluidic Platform with Neural Organoids: Model System for Unraveling Synapses.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00654
Abstract: Unraveling the large number of various signals in the brain under the influence of physical and chemical cues that govern the formation of individual neurons, axons, dendrites, and their functional synapses during the development of… read more here.
Keywords: three dimensional; microfluidic platform; neural organoids; platform neural ... See more keywords
Monkeypox virus spreads from cell-to-cell and leads to neuronal death in human neural organoids
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-61134-0
Abstract: In 2022-23, the world experienced the largest recorded monkeypox virus (MPXV) outbreak outside of endemic regions. Remarkably, cases of neurological manifestations were reported, some of which fatal. MPXV DNA and MPXV-specific antibodies were detected in… read more here.
Keywords: cell cell; neural organoids; human neural; monkeypox virus ... See more keywords
Leptomeningeal Neural Organoid Fusions as Models to Study Meninges-Brain Signaling
Sign Up to like & getrecommendations! Published in 2025 at "Stem Cells and Development"
DOI: 10.1089/scd.2024.0231
Abstract: Neural organoids derived from human-induced pluripotent stem cells (iPSCs) provide a model to study the earliest stages of human brain development, including neurogenesis, neural differentiation, and synaptogenesis. However, neural organoids lack supportive tissues and some… read more here.
Keywords: leptomeningeal neural; brain; meninges brain; neural organoids ... See more keywords
As neural organoids advance, ethics races to keep pace.
Sign Up to like & getrecommendations! Published in 2025 at "Science"
DOI: 10.1126/science.aee0353
Abstract: Scientists, ethicists, and patient advocates mull biology's latest provocative technology. read more here.
Keywords: ethics races; advance ethics; races keep; neural organoids ... See more keywords
Neural Organoids, a Versatile Model for Neuroscience
Sign Up to like & getrecommendations! Published in 2022 at "Molecules and Cells"
DOI: 10.14348/molcells.2022.2019
Abstract: Three-dimensional cultures of human neural tissue/organ-like structures in vitro can be achieved by mimicking the developmental processes occurring in vivo. Rapid progress in the field of neural organoids has fueled the hope (and hype) for… read more here.
Keywords: model neuroscience; organoids versatile; versatile model; neural organoids ... See more keywords