Recapitulation of Neural Crest Specification and EMT via Induction from Neural Plate Border-like Cells
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2020.07.023
Abstract: Summary Neural crest cells (NCCs) contribute to several tissues during embryonic development. NCC formation depends on activation of tightly regulated molecular programs at the neural plate border (NPB) region, which initiate NCC specification and epithelial-to-mesenchymal… read more here.
Keywords: emt; neural plate; plate border; neural crest ... See more keywords
The b-HLH transcription factor Hes3 participates in neural plate border formation by interfering with Wnt/β-catenin signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.07.011
Abstract: Hes3 belongs to the Hes basic helix-loop-helix family of transcriptional repressors that play central roles in maintaining progenitor cells and regulating binary cell fate decisions in the embryo. During Xenopus laevis development, hes3 is expressed… read more here.
Keywords: catenin signaling; neural plate; expression; hes3 ... See more keywords
Involvement of an Oct4-related PouV gene, pou5f3/pou2, in neurogenesis in the early neural plate of zebrafish embryos.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2019.09.002
Abstract: In early vertebrate embryos, the dorsal ectoderm is induced by the axial mesendoderm to form the neural plate, which is given competence to form neural cells by soxB1 genes. Subsequently, neurogenesis proceeds in proneural clusters… read more here.
Keywords: oct4 related; neural plate; early neural; gene ... See more keywords
Frizzled3 inhibits Vangl2-Prickle3 association to establish planar cell polarity in the vertebrate neural plate.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.258864
Abstract: The orientation of epithelial cells in the plane of the tissue, known as planar cell polarity (PCP), is regulated by interactions of asymmetrically localized PCP protein complexes. In the Xenopus neural plate, Van Gogh-like2 (Vangl2)… read more here.
Keywords: cell polarity; neural plate; planar cell; cell ... See more keywords
Repressive Interactions Between Transcription Factors Separate Different Embryonic Ectodermal Domains
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.786052
Abstract: The embryonic ectoderm is composed of four domains: neural plate, neural crest, pre-placodal region (PPR) and epidermis. Their formation is initiated during early gastrulation by dorsal-ventral and anterior-posterior gradients of signaling factors that first divide… read more here.
Keywords: cell; neural crest; embryonic ectodermal; neural plate ... See more keywords
Folate Carrier Deficiency Drives Differential Methylation and Enhanced Cellular Potency in the Neural Plate Border
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.834625
Abstract: The neural plate border (NPB) of vertebrate embryos segregates from the neural and epidermal regions, and it is comprised of an intermingled group of multipotent progenitor cells. Folate is the precursor of S-adenosylmethionine, the main… read more here.
Keywords: methylation; deficiency drives; folate carrier; neural plate ... See more keywords
Dynamic transcriptional signature and cell fate analysis reveals plasticity of individual neural plate border cells
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.21620
Abstract: The ‘neural plate border’ of vertebrate embryos contains precursors of neural crest and placode cells, both defining vertebrate characteristics. How these lineages segregate from neural and epidermal fates has been a matter of debate. We… read more here.
Keywords: border cells; analysis; neural plate; plate border ... See more keywords
Single-cell atlas of early chick development reveals gradual segregation of neural crest lineage from the neural plate border during neurulation
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.74464
Abstract: The epiblast of vertebrate embryos is comprised of neural and non-neural ectoderm, with the border territory at their intersection harboring neural crest and cranial placode progenitors. Here, we a generate single-cell atlas of the developing… read more here.
Keywords: neurulation; neural crest; border; neural plate ... See more keywords