Articles with "neural precursor" as a keyword



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Role of the hydrogen sulfide‐releasing donor ADT‐OH in the regulation of mammal neural precursor cells

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Published in 2022 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.30726

Abstract: Neural precursor cells (NPCs) generate new neurons to supplement neuronal loss as well as to repair damaged neural circuits. Therefore, NPCs have potential applications in a variety of neurological diseases, such as spinal cord injury,… read more here.

Keywords: precursor cells; sulfide releasing; hydrogen sulfide; neural precursor ... See more keywords
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Tissue Engineered Neural Constructs Composed of Neural Precursor Cells, Recombinant Spidroin and PRP for Neural Tissue Regeneration

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-39341-9

Abstract: We have designed a novel two-component matrix (SPRPix) for the encapsulation of directly reprogrammed human neural precursor cells (drNPC). The matrix is comprised of 1) a solid anisotropic complex scaffold prepared by electrospinning a mixture… read more here.

Keywords: neural tissue; tissue; tissue engineered; prp ... See more keywords
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Neural precursor cells form integrated brain-like tissue when implanted into rat cerebrospinal fluid

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Published in 2018 at "Communications Biology"

DOI: 10.1038/s42003-018-0113-8

Abstract: There is tremendous interest in transplanting neural precursor cells for brain tissue regeneration. However, it remains unclear whether a vascularized and integrated complex neural tissue can be generated within the brain through transplantation of cells.… read more here.

Keywords: tissue; brain; brain like; neural precursor ... See more keywords
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Human iPSC‐derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model

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Published in 2021 at "Cell Proliferation"

DOI: 10.1111/cpr.13082

Abstract: To investigate whether human HLA‐homozygous induced pluripotent stem cell (iPSC)‐derived neural precursor cells (iPSC‐NPCs) can provide functional benefits in Huntington’s disease (HD), we transplanted them into the YAC128 transgenic HD mouse model. read more here.

Keywords: cell; disease; derived neural; ipsc derived ... See more keywords
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Exogenous Neural Precursor Cell Transplantation Results in Structural and Functional Recovery in a Hypoxic-Ischemic Hemiplegic Mouse Model

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Published in 2018 at "eNeuro"

DOI: 10.1523/eneuro.0369-18.2018

Abstract: Abstract Cerebral palsy (CP) is a common pediatric neurodevelopmental disorder, frequently resulting in motor and developmental deficits and often accompanied by cognitive impairments. A regular pathobiological hallmark of CP is oligodendrocyte maturation impairment resulting in… read more here.

Keywords: recovery; cell; hemiplegic mouse; transplantation ... See more keywords
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Charge-Balanced Electrical Stimulation Can Modulate Neural Precursor Cell Migration in the Presence of Endogenous Electric Fields in Mouse Brains

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Published in 2019 at "eNeuro"

DOI: 10.1523/eneuro.0382-19.2019

Abstract: Abstract Electric fields (EFs) can direct cell migration and are crucial during development and tissue repair. We previously reported neural precursor cells (NPCs) are electrosensitive cells that can undergo rapid and directed migration towards the… read more here.

Keywords: neural precursor; cell; charge balanced; electrical stimulation ... See more keywords
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IL-6-Mediated Upregulated miRNAs in Extracellular Vesicles Derived from Lund Human Mesencephalic (LUHMES) Cells: Effects on Astrocytes and Microglia

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Published in 2023 at "Biomolecules"

DOI: 10.3390/biom13050718

Abstract: Psychological stress plays a major role in depression, and interleukin-6 (IL-6) is elevated during depression and psychological stress. MicroRNAs (miRNAs) in extracellular vesicles (EVs), including exosomes and microvesicles, suppress mRNA expression in other cells when… read more here.

Keywords: extracellular vesicles; mirnas extracellular; mediated upregulated; hsa ... See more keywords
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A Comprehensive Stemness Gene Expression Analysis Signifies the Role of ABC Transporters and Molecular Chaperons in Determining the Fate of Human Neural Precursor Cells

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Published in 2022 at "Neurology India"

DOI: 10.4103/0028-3886.349631

Abstract: Background and Aim: The major aim of this study was to identify the most common stemness genes across different stem cell types and further validate them in human fetal subventricular zone-derived primary and cultured neural… read more here.

Keywords: precursor cells; gene signatures; analysis; meta gene ... See more keywords