Role of the hydrogen sulfide‐releasing donor ADT‐OH in the regulation of mammal neural precursor cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30726
Abstract: Neural precursor cells (NPCs) generate new neurons to supplement neuronal loss as well as to repair damaged neural circuits. Therefore, NPCs have potential applications in a variety of neurological diseases, such as spinal cord injury,… read more here.
Keywords: precursor cells; sulfide releasing; hydrogen sulfide; neural precursor ... See more keywords
RNA-Seq time-course analysis of neural precursor cell transcriptome in response to herpes simplex Virus-1 infection
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Neurovirology"
DOI: 10.1007/s13365-024-01198-8
Abstract: The neurogenic niches within the central nervous system serve as essential reservoirs for neural precursor cells (NPCs), playing a crucial role in neurogenesis. However, these NPCs are particularly vulnerable to infection by the herpes simplex… read more here.
Keywords: time; rna seq; herpes simplex; infection ... See more keywords
Tissue Engineered Neural Constructs Composed of Neural Precursor Cells, Recombinant Spidroin and PRP for Neural Tissue Regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-39341-9
Abstract: We have designed a novel two-component matrix (SPRPix) for the encapsulation of directly reprogrammed human neural precursor cells (drNPC). The matrix is comprised of 1) a solid anisotropic complex scaffold prepared by electrospinning a mixture… read more here.
Keywords: neural tissue; tissue; tissue engineered; prp ... See more keywords
Neural precursor cells form integrated brain-like tissue when implanted into rat cerebrospinal fluid
Sign Up to like & getrecommendations! Published in 2018 at "Communications Biology"
DOI: 10.1038/s42003-018-0113-8
Abstract: There is tremendous interest in transplanting neural precursor cells for brain tissue regeneration. However, it remains unclear whether a vascularized and integrated complex neural tissue can be generated within the brain through transplantation of cells.… read more here.
Keywords: tissue; brain; brain like; neural precursor ... See more keywords
Human iPSC‐derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model
Sign Up to like & getrecommendations! Published in 2021 at "Cell Proliferation"
DOI: 10.1111/cpr.13082
Abstract: To investigate whether human HLA‐homozygous induced pluripotent stem cell (iPSC)‐derived neural precursor cells (iPSC‐NPCs) can provide functional benefits in Huntington’s disease (HD), we transplanted them into the YAC128 transgenic HD mouse model. read more here.
Keywords: cell; disease; derived neural; ipsc derived ... See more keywords
Thyroid hormone promotes fetal neurogenesis
Sign Up to like & getrecommendations! Published in 2025 at "JCI Insight"
DOI: 10.1172/jci.insight.194445
Abstract: Maternal low thyroxine (T4) serum levels during the first trimester of pregnancy correlate with cerebral cortex volume and mental development of the progeny, but why neural cells during early fetal brain development are vulnerable to… read more here.
Keywords: neural precursor; fetal neurogenesis; thyroid hormone; hormone ... See more keywords
Ubiquitination of angiotensin-converting enzyme 2 contributes to the development of pulmonary arterial hypertension mediated by neural precursor cell–expressed developmentally down-regulated gene 4-Like
Sign Up to like & getrecommendations! Published in 2024 at "Respiratory Research"
DOI: 10.1186/s12931-024-02953-5
Abstract: In this study, we investigated whether neural precursor cell–expressed developmentally down-regulated gene 4-like (NEDD4L) is the E3 enzyme of angiotensin-converting enzyme 2 (ACE2) and whether NEDD4L degrades ACE2 via ubiquitination, leading to the progression of… read more here.
Keywords: ubiquitination; pulmonary arterial; cell expressed; precursor cell ... See more keywords
The bidirectional role of GABAA and GABAB receptors during the differentiation process of neural precursor cells of the subventricular zone
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0305853
Abstract: The intricate process of neuronal differentiation integrates multiple signals to induce transcriptional, morphological, and electrophysiological changes that reshape the properties of neural precursor cells during their maturation and migration process. An increasing number of neurotransmitters… read more here.
Keywords: neural precursor; subventricular zone; differentiation process; precursor cells ... See more keywords
Exogenous Neural Precursor Cell Transplantation Results in Structural and Functional Recovery in a Hypoxic-Ischemic Hemiplegic Mouse Model
Sign Up to like & getrecommendations! Published in 2018 at "eNeuro"
DOI: 10.1523/eneuro.0369-18.2018
Abstract: Abstract Cerebral palsy (CP) is a common pediatric neurodevelopmental disorder, frequently resulting in motor and developmental deficits and often accompanied by cognitive impairments. A regular pathobiological hallmark of CP is oligodendrocyte maturation impairment resulting in… read more here.
Keywords: recovery; cell; hemiplegic mouse; transplantation ... See more keywords
Charge-Balanced Electrical Stimulation Can Modulate Neural Precursor Cell Migration in the Presence of Endogenous Electric Fields in Mouse Brains
Sign Up to like & getrecommendations! Published in 2019 at "eNeuro"
DOI: 10.1523/eneuro.0382-19.2019
Abstract: Abstract Electric fields (EFs) can direct cell migration and are crucial during development and tissue repair. We previously reported neural precursor cells (NPCs) are electrosensitive cells that can undergo rapid and directed migration towards the… read more here.
Keywords: neural precursor; cell; charge balanced; electrical stimulation ... See more keywords
IL-6-Mediated Upregulated miRNAs in Extracellular Vesicles Derived from Lund Human Mesencephalic (LUHMES) Cells: Effects on Astrocytes and Microglia
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13050718
Abstract: Psychological stress plays a major role in depression, and interleukin-6 (IL-6) is elevated during depression and psychological stress. MicroRNAs (miRNAs) in extracellular vesicles (EVs), including exosomes and microvesicles, suppress mRNA expression in other cells when… read more here.
Keywords: extracellular vesicles; mirnas extracellular; mediated upregulated; hsa ... See more keywords