Convergent and distributed effects of the 3q29 deletion on the human neural transcriptome
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01435-2
Abstract: The 3q29 deletion (3q29Del) confers high risk for schizophrenia and other neurodevelopmental and psychiatric disorders. However, no single gene in this interval is definitively associated with disease, prompting the hypothesis that neuropsychiatric sequelae emerge upon… read more here.
Keywords: 3q29 genes; 3q29 deletion; human neural; convergent distributed ... See more keywords
Regulation of the Alternative Neural Transcriptome by ELAV/Hu RNA Binding Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.848626
Abstract: The process of alternative polyadenylation (APA) generates multiple 3' UTR isoforms for a given locus, which can alter regulatory capacity and on occasion change coding potential. APA was initially characterized for a few genes, but… read more here.
Keywords: rna binding; neural transcriptome; regulation alternative; binding proteins ... See more keywords