Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors and status of novel antivirals, 2016–2017
Sign Up to like & getrecommendations! Published in 2018 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2018.07.001
Abstract: A total of 13672 viruses, collected by World Health Organization recognised National Influenza Centres between May 2016 and May 2017, were assessed for neuraminidase inhibitor susceptibility by four WHO Collaborating Centres for Reference and Research… read more here.
Keywords: susceptibility; global update; influenza; neuraminidase inhibitor ... See more keywords
Influenza B viruses from different genetic backgrounds are variably impaired by neuraminidase inhibitor resistance-associated substitutions.
Sign Up to like & getrecommendations! Published in 2019 at "Antiviral research"
DOI: 10.1016/j.antiviral.2019.104669
Abstract: Identifying evolutionary routes to antiviral resistance among influenza viruses informs molecular-based resistance surveillance and clinical decisions. To improve antiviral management and understand whether clinically identified neuraminidase (NA) inhibitor (NAI) resistance-associated markers affect influenza B viruses… read more here.
Keywords: influenza viruses; viruses different; neuraminidase inhibitor; resistance ... See more keywords
Benefit of Early Initiation of Neuraminidase Inhibitor Treatment to Hospitalized Patients With Avian Influenza A(H7N9) Virus
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DOI: 10.1093/cid/cix930
Abstract: Background The significance of early neuraminidase inhibitor (NAI) therapy for treating influenza A(H7N9) is currently unknown. Methods The duration of viral shedding was monitored by reverse-transcription polymerase chain reaction after patients with confirmed H7N9 infection… read more here.
Keywords: viral shedding; within days; influenza h7n9; nai therapy ... See more keywords
Neonatal outcomes after neuraminidase inhibitor use during pregnancy: a meta-analysis of cohort studies.
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DOI: 10.1111/bcp.15033
Abstract: AIM Influenza infection poses a severe threat to pregnant mothers, and antiviral treatment is recommended. However, the safety of neuraminidase-inhibitor antiviral medications during pregnancy has not been well described. METHODS A systematic review and meta-analysis… read more here.
Keywords: pregnancy; inhibitor; neuraminidase inhibitor; exposure neuraminidase ... See more keywords
Characterization of neuraminidase inhibitor-resistant influenza virus isolates from immunocompromised patients in the Republic of Korea
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DOI: 10.1186/s12985-020-01375-1
Abstract: Background The emergence of influenza viruses resistant to anti-influenza drugs is a threat to global public health. The Korea Centers for Disease Control and Prevention operates the Korea Influenza and Respiratory Viruses Surveillance System (KINRESS)… read more here.
Keywords: influenza viruses; influenza; neuraminidase inhibitor; influenza virus ... See more keywords
Association between Maoto Use and Hospitalization for Seasonal Influenza in a Nonelderly Cohort in Japan.
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DOI: 10.2169/internalmedicine.6416-20
Abstract: Objective Maoto is a traditional Japanese Kampo formula used to treat influenza. However, clinical evidence for maoto has been limited to small-scale studies of its effect in alleviating symptoms. The present study evaluated whether or… read more here.
Keywords: hospitalization; maoto; neuraminidase inhibitor; influenza ... See more keywords
Neuraminidase Inhibitor of Garcinia atroviridis L. Fruits and Leaves Using Partial Purification and Molecular Characterization
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DOI: 10.3390/molecules27030949
Abstract: Neuraminidase (NA) is an enzyme that prevents virions from aggregating within the host cell and promotes cell-to-cell spread by cleaving glycosidic linkages to sialic acid. The best-known neuraminidase is the viral neuraminidase, which present in… read more here.
Keywords: garcinia; neuraminidase; garcinia acid; neuraminidase inhibitor ... See more keywords