Aripiprazole and haloperidol protect neurite lesions via reducing excessive D2R-DISC1 complex formation
Sign Up to like & getrecommendations! Published in 2019 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2018.12.007
Abstract: &NA; Dopamine D2 receptor (D2R) hyperactivity causes altered brain development and later produces onset of symptoms mimicking schizophrenia. It is known that D2R interacts with disrupted in schizophrenia 1 (DISC1); however, the effect of D2R‐DISC1… read more here.
Keywords: hyperactivity; haloperidol; neurite lesions; disc1 ... See more keywords
Propionate Protects Haloperidol-Induced Neurite Lesions Mediated by Neuropeptide Y
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2018.00743
Abstract: Haloperidol is a commonly used antipsychotic drug for treating schizophrenia. Clinical imaging studies have found that haloperidol can cause volume loss of human brain tissue, which is supported by animal studies showing that haloperidol reduces… read more here.
Keywords: haloperidol induced; induced neurite; propionate; effect ... See more keywords