Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
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DOI: 10.1101/2022.11.01.513927
Abstract: Mitochondrial dysfunction and axon loss are hallmarks of neurologic diseases. Gasdermin (GSDM) proteins are executioner pore-forming molecules that mediate cell death, yet their roles in the central nervous system (CNS) are not well understood. Here,… read more here.
Keywords: loss; gsdme; neurite loss; motor ... See more keywords