Integration of Phase-Change Materials with Electrospun Fibers for Promoting Neurite Outgrowth under Controlled Release.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced functional materials"
DOI: 10.1002/adfm.201705563
Abstract: We report a temperature-regulated system for the controlled release of nerve growth factor (NGF) to promote neurite outgrowth. The system is based upon microparticles fabricated using coaxial electrospray, with the outer solution containing a phase-change… read more here.
Keywords: phase change; neurite outgrowth; controlled release; release ... See more keywords
Positive effect of Astragaloside IV on neurite outgrowth via talin‐dependent integrin signaling and microfilament force
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30002
Abstract: Integrin plays a prominent role in neurite outgrowth by transmitting both mechanical and chemical signals. Integrin expression is closely associated with Astragaloside IV (AS‐IV), the main component extracted from Astragali radix, which has a positive… read more here.
Keywords: neurite outgrowth; integrin; positive effect; microfilament force ... See more keywords
BET protein inhibition in macrophages enhances dorsal root ganglion neurite outgrowth in female mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25036
Abstract: Peripheral nerve regeneration is limited after injury, especially in humans, due to the large distance the axons have to grow in the limbs. This process is highly dependent on the expression of neuroinflammatory factors produced… read more here.
Keywords: female mice; inhibition; root ganglion; neurite outgrowth ... See more keywords
Modeling of Photoreceptor Donor‐Host Interaction Following Transplantation Reveals a Role for Crx, Müller Glia, and Rho/ROCK Signaling in Neurite Outgrowth
Sign Up to like & getrecommendations! Published in 2019 at "STEM CELLS"
DOI: 10.1002/stem.2985
Abstract: The goal of photoreceptor transplantation is to establish functional synaptic connectivity between donor cells and second‐order neurons in the host retina. There is, however, limited evidence of donor‐host photoreceptor connectivity post‐transplant. In this report, we… read more here.
Keywords: donor host; ller glia; donor; neurite outgrowth ... See more keywords
Talaumidin Promotes Neurite Outgrowth of Staurosporine-Differentiated RGC-5 Cells Through PI3K/Akt-Dependent Pathways.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-75402-4_79
Abstract: Talaumidin, a tetrahydrofuran neolignan isolated from the root of Aristolochia arcuata, was an interesting small molecule with neurotrophic activity in the cultured neuron. Talaumidin can promote neurite outgrowth from neurons. However, the mechanism by which… read more here.
Keywords: talaumidin promotes; talaumidin; promotes neurite; neurite outgrowth ... See more keywords
Transcriptional regulation of CRMP5 controls neurite outgrowth through Sox5
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2634-6
Abstract: Transcriptional regulation of proteins involved in neuronal polarity is a key process that underlies the ability of neurons to transfer information in the central nervous system. The Collapsin Response Mediator Protein (CRMP) family is best… read more here.
Keywords: crmp5; neurite outgrowth; sox5; transcriptional regulation ... See more keywords
A screened PirB antagonist peptide antagonizes Aβ42-mediated inhibition of neurite outgrowth in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-021-11363-2
Abstract: Alzheimer's disease (AD) is a type of progressive neurodegenerative disease, and amyloid β-protein 42 (Aβ42) serves an important role in the pathological process of development of AD. Paired immunoglobulin-like receptor B (PirB) is a functional… read more here.
Keywords: outgrowth vitro; antagonist peptide; pap11; neurite outgrowth ... See more keywords
Loss of the basic helix-loop-helix transcription factor Bhlhe41 induces cell death and impairs neurite outgrowth in Neuro2a cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-018-3383-z
Abstract: The basic helix-loop-helix (bHLH) superfamily of transcription factors have been implicated in a wide range of cellular functions such as proliferation, differentiation, tumorigenesis, and circadian rhythms. In a previous siRNA-based screen, bHLH family member e41… read more here.
Keywords: bhlhe41; loop helix; helix loop; neurite outgrowth ... See more keywords
Somatostatin-Mediated Changes in Microtubule-Associated Proteins and Retinoic Acid–Induced Neurite Outgrowth in SH-SY5Y Cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-019-01291-2
Abstract: Somatostatin (SST) is a growth hormone inhibitory peptide involved in regulation of several physiological responses of cells including neurotransmission, cell migration, maturation, and neurite formation. In the present study, we examined the role of SST… read more here.
Keywords: sst; neurite outgrowth; sy5y cells; outgrowth sy5y ... See more keywords
Differential Regulation of Neurite Outgrowth and Growth Cone Morphology by 3D Fibronectin and Fibronectin-Collagen Extracellular Matrices.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02637-x
Abstract: The extracellular matrix (ECM) plays a critical role in development, homeostasis, and regeneration of tissue structures and functions. Cell interactions with the ECM are dynamic and cells respond to ECM remodeling by changes in morphology… read more here.
Keywords: fibronectin; growth cone; matrix; growth ... See more keywords
Assessing the combination of magnetic field stimulation, iron oxide nanoparticles, and aligned electrospun fibers for promoting neurite outgrowth from dorsal root ganglia in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.06.049
Abstract: Magnetic fiber composites combining superparamagnetic iron oxide nanoparticles (SPIONs) and electrospun fibers have shown promise in tissue engineering fields. Controlled grafting of SPIONs to the fibers post-electrospinning generates biocompatible magnetic composites without altering desired fiber… read more here.
Keywords: outgrowth; aligned electrospun; electrospun fibers; neurite outgrowth ... See more keywords