Oral nimodipine treatment has no effect on amyloid pathology or neuritic dystrophy in the 5XFAD mouse model of amyloidosis
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DOI: 10.1371/journal.pone.0263332
Abstract: Dysregulation of calcium homeostasis has been hypothesized to play a role in Alzheimer’s disease (AD) pathogenesis. Increased calcium levels can impair axonal transport, disrupt synaptic transmission, and ultimately lead to cell death. Given the potential… read more here.
Keywords: calcium; amyloid pathology; neuritic dystrophy; pathology ... See more keywords