Cadmium induces actin cytoskeleton alterations and dysfunction in Neuro‐2a cells
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22700
Abstract: Cadmium (Cd) is considered a possible etiological factor in neurodegenerative diseases. However, the exact mechanism by which Cd induces neurotoxicity is not well elucidated. In this study, Neuro‐2a cells were treated with 0, 10, 20,… read more here.
Keywords: actin cytoskeleton; neuro cells; cadmium; cytoskeleton alterations ... See more keywords
Role of cell surface vimentin in Chandipura virus replication in Neuro-2a cells
Sign Up to like & getrecommendations! Published in 2020 at "Virus Research"
DOI: 10.1016/j.virusres.2020.198014
Abstract: Abstract The neurotropic behavior of Chandipura virus (CHPV) is partly understood in experimental animals. Under in vitro conditions, neuronal cells could be a useful tool to study the CHPV interaction with neuronal proteins. The information… read more here.
Keywords: vimentin; surface vimentin; chpv; neuro cells ... See more keywords
Chemical Proteomics Reveals Off-Targets of the Anandamide Reuptake Inhibitor WOBE437
Sign Up to like & getrecommendations! Published in 2022 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.2c00122
Abstract: Anandamide or N-arachidonoylethanolamine (AEA) is a signaling lipid that modulates neurotransmitter release via activation of the type 1 cannabinoid receptor (CB1R) in the brain. Termination of anandamide signaling is thought to be mediated via a… read more here.
Keywords: wobe437; reveals targets; inhibitor; neuro cells ... See more keywords
Monascus pigment rubropunctatin derivative FZU-H reduces Aβ(1-42)-induced neurotoxicity in Neuro-2A cells
Sign Up to like & getrecommendations! Published in 2018 at "RSC Advances"
DOI: 10.1039/c8ra02365d
Abstract: Alzheimer's disease (AD) is an extremely complex disease, characterized by several pathological features including oxidative stress and amyloid-β (Aβ) aggregation. Blockage of Aβ-induced injury has emerged as a potential therapeutic approach for AD. Our previous… read more here.
Keywords: neuro cells; rubropunctatin derivative; derivative fzu; pigment rubropunctatin ... See more keywords
The Metabolite Urolithin-A Ameliorates Oxidative Stress in Neuro-2a Cells, Becoming a Potential Neuroprotective Agent
Sign Up to like & getrecommendations! Published in 2020 at "Antioxidants"
DOI: 10.3390/antiox9020177
Abstract: Urolithin A is a metabolite generated from ellagic acid and ellagitannins by the intestinal microbiota after consumption of fruits such as pomegranates or strawberries. The objective of this study was to determine the cytoprotective capacity… read more here.
Keywords: direct radical; neuro cells; stress; metabolite urolithin ... See more keywords
Protective Potential of β-Hydroxybutyrate against Glucose-Deprivation-Induced Neurotoxicity Involving the Modulation of Autophagic Flux and the Monomeric Aβ Level in Neuro-2a Cells
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11030698
Abstract: Hypoglycemia has been known as a potential contributory factor to neurodegenerative diseases, such as Alzheimer’s disease. There may be shared pathogenic mechanisms underlying both conditions, and the ketone body, β-hydroxybutyrate (BHB), as an alternative substrate… read more here.
Keywords: glucose deprivation; deprivation; autophagic flux; neuro cells ... See more keywords
Recombinant Analogs of Sea Anemone Kunitz-Type Peptides Influence P2X7 Receptor Activity in Neuro-2a Cells
Sign Up to like & getrecommendations! Published in 2023 at "Marine Drugs"
DOI: 10.3390/md21030192
Abstract: Purinergic P2X7 receptors (P2X7) have now been proven to play an important role and represent an important therapeutic target in many pathological conditions including neurodegeneration. Here, we investigated the impact of peptides on purinergic signaling… read more here.
Keywords: type peptides; receptor; neuro cells; kunitz type ... See more keywords