LRP1 deficiency in microglia blocks neuro‐inflammation in the spinal dorsal horn and neuropathic pain processing
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DOI: 10.1002/glia.23599
Abstract: Following injury to the peripheral nervous system (PNS), microglia in the spinal dorsal horn (SDH) become activated and contribute to the development of local neuro‐inflammation, which may regulate neuropathic pain processing. The molecular mechanisms that… read more here.
Keywords: microglia; neuro inflammation; lrp1; neuropathic pain ... See more keywords
Microglial AIM2 alleviates antiviral‐related neuro‐inflammation in mouse models of Parkinson's disease
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DOI: 10.1002/glia.24260
Abstract: Inflammasome involvement in Parkinson's disease (PD) has been intensively investigated. Absent in melanoma 2 (AIM2) is an essential inflammasome protein known to contribute to the development of several neurological diseases. However, a specific role for… read more here.
Keywords: aim2; neuro inflammation; mouse; antiviral related ... See more keywords
Neutrophil-to-lymphocyte ratio: a marker of neuro-inflammation in multiple sclerosis?
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neurology"
DOI: 10.1007/s00415-020-10322-7
Abstract: Background The significance of neutrophil-to-lymphocyte ratio (NLR) has been explored in different diseases. Few studies addressed its role in patients with multiple sclerosis (MS), with promising results regarding its association with disease activity or disability.… read more here.
Keywords: neuro inflammation; neutrophil lymphocyte; multiple sclerosis; lymphocyte ratio ... See more keywords
Berberine attenuates depressive-like behaviors by suppressing neuro-inflammation in stressed mice
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DOI: 10.1016/j.brainresbull.2017.08.008
Abstract: Berberine, the major constituent alkaloid originally from the famous Chinese herb Huanglian (Coptis chinensis), has been shown to exert antidepressant-like effects in rodents. However, it is still not clear the involvement of neuro-inflammation suppression in… read more here.
Keywords: suppressing neuro; neuro inflammation; like behaviors; depressive like ... See more keywords
Neuro-inflammation et atteintes du cerveau du prématuré
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DOI: 10.1016/j.morpho.2019.09.052
Abstract: Les naissances prematurees placent les nourrissons dans un environnement defavorable entrainant un developpement cerebral anormal et des lesions cerebrales par le biais d’un mecanisme mal compris, mais connu pour impliquer une neuro-inflammation. Une approche originale… read more here.
Keywords: chez; inflammation atteintes; neuro inflammation; inflammation ... See more keywords
Biological profiling of prospective antidepressant response in major depressive disorder: Associations with (neuro)inflammation, fatty acid metabolism, and amygdala-reactivity
Sign Up to like & getrecommendations! Published in 2017 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2017.02.019
Abstract: BACKGROUND A better understanding of factors underlying antidepressant non-response may improve the prediction of which patients will respond to what treatment. Major depressive disorder (MDD) is associated with alterations in fatty acid metabolism, (neuro)inflammation and… read more here.
Keywords: neuro inflammation; amygdala reactivity; response; antidepressant response ... See more keywords
Dioscin relieves endotoxemia induced acute neuro-inflammation and protect neurogenesis via improving 5-HT metabolism
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DOI: 10.1038/srep40035
Abstract: Sepsis, in addition to causing fatality, is an independent risk factor for cognitive impairment among sepsis survivors. The pathologic mechanism of endotoxemia induced acute neuro-inflammation still has not been fully understood. For the first time,… read more here.
Keywords: endotoxemia induced; acute neuro; neuro inflammation; inflammation ... See more keywords
Longxuetongluo capsule alleviates LPS-induced neuro-inflammation by regulating multiple signaling pathways in BV2 microglia cells.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000258
Abstract: BACKGROUND Longxuetongluo capsule (LTC), derived from the total phenolic compounds of Chinese dragon's blood, is now used to treatment of ischemic stroke in convalescence. The aim of this study is to explore the neuroprotective effect… read more here.
Keywords: microglia cells; longxuetongluo capsule; bv2 microglia; signaling pathways ... See more keywords
PET Imaging of Neuro-Inflammation with Tracers Targeting the Translocator Protein (TSPO), a Systematic Review: From Bench to Bedside
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DOI: 10.3390/diagnostics13061029
Abstract: Parkinson’s disease is the second most common neurodegenerative disorder, affecting 2–3% of the population of patients >65 years. Although the standard diagnosis of PD is clinical, neuroimaging plays a key role in the evaluation of… read more here.
Keywords: neuro inflammation; inflammation tracers; imaging neuro; neurodegenerative disorders ... See more keywords
Neuro-Inflammation Modulation and Post-Traumatic Brain Injury Lesions: From Bench to Bed-Side
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DOI: 10.3390/ijms231911193
Abstract: Head trauma is the most common cause of disability in young adults. Known as a silent epidemic, it can cause a mosaic of symptoms, whether neurological (sensory–motor deficits), psychiatric (depressive and anxiety symptoms), or somatic… read more here.
Keywords: traumatic brain; neuro inflammation; brain; inflammation modulation ... See more keywords
Neuroprotective effect of tormentic acid against memory impairment and neuro-inflammation in an Alzheimer's disease mouse model
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DOI: 10.3892/mmr.2020.11154
Abstract: Cognitive impairment and neuro-inflammatory responses are the distinctive characteristics of Alzheimer's disease (AD). Tormentic acid (TA) is one of the major active components of Potentilla chinensis and has been demonstrated to have anti-inflammatory properties. However,… read more here.
Keywords: neuro inflammation; impairment; memory impairment; impairment neuro ... See more keywords