Of Mice and Men: Comparative Analysis of Neuro-Inflammatory Mechanisms in Human and Mouse Using Cause-and-Effect Models
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Alzheimer's Disease"
DOI: 10.3233/jad-170255
Abstract: Perturbance in inflammatory pathways have been identified as one of the major factors which leads to neurodegenerative diseases (NDD). Owing to the limited access of human brain tissues and the immense complexity of the brain,… read more here.
Keywords: comparative analysis; mouse models; mice men; neuro inflammatory ... See more keywords
Microbial Immuno-Communication in Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2017.00151
Abstract: Neuro-inflammation is a critical process by which the brain coordinates chemokine-regulated cellular recruitment, cytokine release, and cell-mediated removal of pathogenic material to protect against infection or brain injury. Dysregulation of this immune response is involved… read more here.
Keywords: host microbiome; microbial immuno; neurodegenerative diseases; neuro inflammatory ... See more keywords
The Neuro-Inflammatory-Vascular Circuit: Evidence for a Sex-Dependent Interrelation?
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2020.614345
Abstract: Cardiovascular disease (CVD) is the leading cause of death worldwide with mortality rates in women currently exceeding those in men. To date, evidence is widely lacking for unique female determinants of CVD. However, strong associations… read more here.
Keywords: sex dependent; evidence; sex; neuro inflammatory ... See more keywords
Combining S100B and Cytokines as Neuro-Inflammatory Biomarkers for Diagnosing Generalized Anxiety Disorder: A Proof-of-Concept Study Based on Machine Learning
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.881241
Abstract: Introduction S100 calcium-binding protein B (S100B) is a neurotrophic factor that regulates neuronal growth and plasticity by activating astrocytes and microglia through the production of cytokines involved in Generalized Anxiety Disorder (GAD). However, few studies… read more here.
Keywords: inflammatory biomarkers; neuro inflammatory; s100b cytokines; machine learning ... See more keywords
Next Generation Sequencing of Cerebrospinal Fluid B Cell Repertoires in Multiple Sclerosis and Other Neuro-Inflammatory Diseases—A Comprehensive Review
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostics"
DOI: 10.3390/diagnostics11101871
Abstract: During the last few decades, the role of B cells has been well established and redefined in neuro-inflammatory diseases, including multiple sclerosis and autoantibody-associated diseases. In particular, B cell maturation and trafficking across the blood–brain… read more here.
Keywords: bbb; inflammatory diseases; multiple sclerosis; neuro inflammatory ... See more keywords
Ginkgo biloba preparation prevents and treats senile dementia by inhibiting neuro-inflammatory responses
Sign Up to like & getrecommendations! Published in 2019 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v17i10.10
Abstract: Purpose: To study the effect of Ginkgo biloba preparation on senile dementia and the mechanism of its action. Methods: Sprague Dawley (SD) rat model of chronic cerebral hypoperfusion was produced by vascular occlusion (2-VO). The… read more here.
Keywords: senile dementia; neuro inflammatory; ginkgo biloba; biloba preparation ... See more keywords