Neurobiological insights and novel therapeutic opportunities for CNS disorders from mGlu receptor allosteric and biased modulation
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DOI: 10.1016/j.coph.2016.10.007
Abstract: HIGHLIGHTSSelective ligands have helped define the neurobiological roles of mGlu receptors.Biased agonism/modulation is a key feature of mGlu signaling.Biased signaling should inform future mGlu drug discovery programs. &NA; The metabotropic glutamate (mGlu) receptor family is… read more here.
Keywords: modulation; neurobiological insights; mglu receptor; cns disorders ... See more keywords