The antiepileptic drug levetiracetam promotes neuroblast differentiation and expression of superoxide dismutase in the mouse hippocampal dentate gyrus via PI3K/Akt signalling
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.10.010
Abstract: Levetiracetam (LEV), a second-generation antiepileptic drug, is commonly prescribed to treat certain types of seizures. Few studies have investigated the effects of LEV on hippocampal neurogenesis and its related mechanisms. In the present study, we… read more here.
Keywords: pi3k; neuroblast differentiation; differentiation; mouse hippocampal ... See more keywords
Neuroblast Differentiation-Associated Protein Derived Polypeptides: AHNAK(5758-5775) Induces Inflammation by Activating Mast Cells via ST2
Sign Up to like & getrecommendations! Published in 2022 at "Immunological Investigations"
DOI: 10.1080/08820139.2022.2151368
Abstract: ABSTRACT Psoriasis is a chronic inflammatory skin disease. Mast cells are significantly increased and activated in psoriatic lesions and are involved in psoriatic inflammation. Some endogenous substances can interact with the surface receptors of mast… read more here.
Keywords: differentiation associated; neuroblast differentiation; mast cells; 5758 5775 ... See more keywords
Hypothyroidism increases cyclooxygenase-2 levels and pro-inflammatory response and decreases cell proliferation and neuroblast differentiation in the hippocampus
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2018.8605
Abstract: The present study investigated the effects of hypothyroidism on cyclooxygenase-2 (COX-2) and pro-inflammatory cytokines in the dentate gyrus to elucidate the roles of COX-2 in the hypothyroid hippocampus. Hypothyroidism was induced in rats by treating… read more here.
Keywords: hypothyroidism; levels pro; cell proliferation; neuroblast differentiation ... See more keywords