SLC34A2 promotes neuroblastoma cell stemness via enhancement of miR‐25/Gsk3β‐mediated activation of Wnt/β‐catenin signaling
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DOI: 10.1002/2211-5463.12594
Abstract: Cancer stem cells contribute to cancer progression, but the mechanisms underlying neuroblastoma stem cell development are unclear. Here, we examined the roles of the transcription factor SLC34A2 in regulating the stemness of neuroblastoma cells. We… read more here.
Keywords: stemness; mir gsk3; neuroblastoma cell; neuroblastoma cells ... See more keywords
Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3‐induced mitophagy
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DOI: 10.1002/cam4.2389
Abstract: Neuroblastoma is the second most common pediatric malignancy and has a high rate of spontaneous remission. Uncovering the mechanisms underlying neuroblastoma cell differentiation is critical for therapeutic purposes. A neuroblastoma cell line (N2a) treated with… read more here.
Keywords: hyaluronan synthase; cell differentiation; differentiation; neuroblastoma cell ... See more keywords
Investigation of PP2A and Its Endogenous Inhibitors in Neuroblastoma Cell Survival and Tumor Growth
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DOI: 10.1016/j.tranon.2018.09.011
Abstract: High-risk neuroblastoma continues to carry a poor prognosis. Nearly 50% of these tumors relapse following extensive treatment regimens. Protein phosphatase 2A (PP2A), a tumor suppressor, has been shown to be downregulated in many human cancers… read more here.
Keywords: endogenous inhibitors; pp2a; activation; neuroblastoma cell ... See more keywords
Corrigendum: Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines
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DOI: 10.1038/sdata.2017.183
Abstract: This corrects the article DOI: 10.1038/sdata.2017.33. read more here.
Keywords: profiling commonly; transcriptomic profiling; used neuroblastoma; commonly used ... See more keywords
Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Data"
DOI: 10.1038/sdata.2017.33
Abstract: Neuroblastoma cell lines are an important and cost-effective model used to study oncogenic drivers of the disease. While many of these cell lines have been previously characterized with SNP, methylation, and/or mRNA expression microarrays, there… read more here.
Keywords: used neuroblastoma; cell lines; commonly used; neuroblastoma cell ... See more keywords
Isatin inhibits SH-SY5Y neuroblastoma cell invasion and metastasis through MAO/HIF-1&agr;/CXCR4 signaling
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DOI: 10.1097/cad.0000000000000505
Abstract: Isatin was reported to possess anticancer activities through its effect on tumor proliferation, apoptosis, and metastasis in vitro and in vivo. This study aimed to elucidate the underlying mechanism behind isatin’s ability to inhibit neuroblastoma… read more here.
Keywords: invasion; agr; metastasis; isatin inhibits ... See more keywords
DNA methyltransferase inhibitor 5-azacytidine enhances neuroblastoma cell lysis by an oncolytic parainfluenza virus.
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DOI: 10.1097/cad.0000000000001525
Abstract: Studies with neuroblastoma have shown that the presence of aberrant DNA epigenetic modifications mediated by DNA methyltransferases correlates with poor prognosis, making these enzymes a target for therapeutics based on synthetic epigenetic modulators such as… read more here.
Keywords: neuroblastoma cell; cell; oncolytic parainfluenza; parainfluenza virus ... See more keywords
Alpha-Amylase Inhibits Cell Proliferation and Glucose Uptake in Human Neuroblastoma Cell Lines
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DOI: 10.1155/2022/4271358
Abstract: The present article describes a study of the effects of alpha-amylase (α-amylase) on the human neuroblastoma (NB) cell lines SH-SY5Y, IMR-32, and LA-N-1. NB is the most common malignancy diagnosed in infants younger than 12… read more here.
Keywords: neuroblastoma cell; alpha amylase; cell lines; human neuroblastoma ... See more keywords
N-trans-feruloyltyramine Protects Human Neuroblastoma SK-N-SH Cell Line Against H2O2-Induced Cytotoxicity
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DOI: 10.1177/1934578x221117312
Abstract: Excessive accumulation of reactive oxygen species (ROS) has been regarded as a major contributor of pathogenesis in neurodegenerative diseases. N-trans-feruloyltyramine (NTF), an alkaloid isolated from several plants, has demonstrated an ability to be a potent… read more here.
Keywords: neuroblastoma cell; h2o2 induced; cell line; human neuroblastoma ... See more keywords
Effects mediated by M2 muscarinic orthosteric agonist on cell growth in human neuroblastoma cell lines
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DOI: 10.1515/pac-2018-1224
Abstract: Abstract The role of muscarinic receptors has been largely documented over the past few decades. Recently we demonstrated that the activation of M2 muscarinic receptors arrested cell proliferation and induced apoptosis in glioblastoma and in… read more here.
Keywords: neuroblastoma cell; cell growth; receptor; human neuroblastoma ... See more keywords
trans-4,4'-Dihydroxystilbene (DHS) inhibits human neuroblastoma tumor growth and induces mitochondrial and lysosomal damages in neuroblastoma cell lines.
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DOI: 10.18632/oncotarget.17879
Abstract: In view of the inadequacy of neuroblastoma treatment, five hydroxystilbenes and resveratrol (Resv) were screened for their cytotoxic property against human neuroblastoma cell lines. The mechanism of cytotoxic action of the most potent compound, trans-4,4'-dihydroxystilbene… read more here.
Keywords: neuroblastoma tumor; cell lines; human neuroblastoma; neuroblastoma cell ... See more keywords