Neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene or MYCN gene
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Pathology"
DOI: 10.1136/jcp-2022-208476
Abstract: The MYCN gene belongs to the MYC family of transcription factors. Amplification of MYCN, first discovered in neuroblastoma cells, ushered in the era of cancer genomics. The MYCN gene and MYCN protein are extensively studied… read more here.
Keywords: mycn gene; myc avian; mycn; derived myc ... See more keywords
Small extracellular vesicles induce resistance to anti-GD2 immunotherapy unveiling tipifarnib as an adjunct to neuroblastoma immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-004399
Abstract: Background Anti-GD2 monoclonal antibody immunotherapy has significantly improved the overall survival rate for high-risk neuroblastoma patients. However, 40% of patients fail to respond or develop resistance to treatment, and the molecular mechanisms by which this… read more here.
Keywords: derived sevs; immunotherapy; anti gd2; neuroblastoma ... See more keywords