Monocyte NLRP3-IL-1β Hyperactivation Mediates Neuronal and Synaptic Dysfunction in Perioperative Neurocognitive Disorder.
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DOI: 10.1002/advs.202104106
Abstract: Perioperative neurocognitive disorder may develop in vulnerable patients following major operation. While neuroinflammation is linked to the cognitive effects of surgery, how surgery and immune signaling modulate neuronal circuits, leading to learning and memory impairment… read more here.
Keywords: surgery; perioperative neurocognitive; neurocognitive disorder; neuronal synaptic ... See more keywords
Monitoring HIV-Associated Neurocognitive Disorder Using Screenings: a Critical Review Including Guidelines for Clinical and Research Use
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DOI: 10.1007/s11904-017-0349-9
Abstract: Screening tools to identify HIV-associated neurocognitive disorder (HAND) are primarily devised to detect cognitive impairment on a single occasion. With the chronicity of HIV infection and the risk of HAND developing or progressing despite viral… read more here.
Keywords: use; screening tools; neurocognitive disorder; hand ... See more keywords
TCA cycle metabolic compromise due to an aberrant S-nitrosoproteome in HIV-associated neurocognitive disorder with methamphetamine use.
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DOI: 10.1007/s13365-021-00970-4
Abstract: In the brain, both HIV-1 and methamphetamine (meth) use result in increases in oxidative and nitrosative stress. This redox stress is thought to contribute to the pathogenesis of HIV-associated neurocognitive disorder (HAND) and further worsening… read more here.
Keywords: use; neurocognitive disorder; hiv; tca cycle ... See more keywords
HIV-associated mild neurocognitive disorder (MND)
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DOI: 10.1007/s13760-018-0988-7
Abstract: Abbreviations HIV Human immunodeficiency virus HAD HIV-associated dementia complex MND Mild neurocognitive disorder AIDS Acquired immunodeficiency syndrome HAART Highly active antiretroviral therapy HAND HIV-associated neurocognitive disorders ANI Asymptomatic neurocognitive impairment MRI Magnetic resonance imaging CSF… read more here.
Keywords: neurocognitive disorder; hiv; mild neurocognitive; mnd ... See more keywords
Cannabinoids for major neurocognitive disorder: case report and literature review.
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DOI: 10.1016/j.rcp.2019.07.002
Abstract: INTRODUCTION Major neurocognitive disorder (MNCD) affects millions of people worldwide. However, the pharmacological options for its management are limited, ineffective and frequently associated with severe adverse reactions. CASE REPORT An 85-year-old man with history of… read more here.
Keywords: neurocognitive disorder; disorder; case report; major neurocognitive ... See more keywords
Differential associations between sensory loss and neuropsychiatric symptoms in adults with and without a neurocognitive disorder
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DOI: 10.1017/s1041610217001120
Abstract: ABSTRACT Background: To investigate the differential associations between sensory loss and neuropsychiatric symptoms among older adults with and without diagnosed neurocognitive disorder. Methods: The sample comprised 1,393 adults (52.3% men) aged between 72 and 79… read more here.
Keywords: neurocognitive disorder; sensory loss; neuropsychiatric symptoms; differential associations ... See more keywords
The reliability and validity of DSM 5 diagnostic criteria for neurocognitive disorder and relationship with plasma neurofilament light in a down syndrome population
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DOI: 10.1038/s41598-021-92887-5
Abstract: The validity of dementia diagnostic criteria depends on their ability to distinguish dementia symptoms from pre-existing cognitive impairments. The study aimed to assess inter-rater reliability and concurrent validity of DSM-5 criteria for neurocognitive disorder in… read more here.
Keywords: neurofilament light; neurocognitive disorder; dsm; disorder ... See more keywords
Can individualized-targeted computerized cognitive training improve everyday functioning in adults with HIV-associated neurocognitive disorder?
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DOI: 10.1080/23279095.2021.1906678
Abstract: Half of people with human immunodeficiency virus (HIV) have HIV-associated neurocognitive disorder (HAND). Fortunately, cognitive training programs can improve function across cognitive domains, which may translate to everyday functioning. The Training on Purpose (TOPS) Study… read more here.
Keywords: neurocognitive disorder; training; cognitive training; everyday functioning ... See more keywords
Safety and efficacy of Jujadokseo-hwan for memory deficit (amnesia) in mild neurocognitive disorder
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DOI: 10.1097/md.0000000000019231
Abstract: BACKGROUND Mild neurocognitive disorder (mNCD) is one of the degenerative diseases that results in memory deficit, and can progress to dementia. The effectiveness of drug therapy for mNCD is still debatable, but treatment of this… read more here.
Keywords: medicine; efficacy; test; mild neurocognitive ... See more keywords
Differential hippocampal protein expression between normal mice and mice with the perioperative neurocognitive disorder: a proteomic analysis
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DOI: 10.1186/s40001-021-00599-3
Abstract: Objectives To compare differential expression protein in hippocampal tissues from mice of perioperative neurocognitive disorder (PND) and normal control mice and to explore the possible mechanism of PND. Methods Mice were randomly divided into a… read more here.
Keywords: perioperative neurocognitive; neurocognitive disorder; mice perioperative; expression ... See more keywords
Alterations in blink and masseter reflex latencies in older adults with neurocognitive disorder and/or diabetes mellitus
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DOI: 10.12998/wjcc.v10.i1.177
Abstract: BACKGROUND Blink and masseter reflexes provide reliable, quantifiable data on the function of the central nervous system: Delayed latencies have been found in patients with neurocognitive disorder (ND) and type 2 diabetes mellitus (T2DM), but… read more here.
Keywords: blink masseter; older adults; masseter; masseter reflex ... See more keywords